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CAS: 535-80-8
分子式: C7H5ClO2
分子量: 156.57
沸点: 274-276°C
熔点: 154-157℃
中文名称: 
3-氯苯甲酸
间氯苯甲酸
英文名称: 
acido m-clorobenzoico
acido m-clorobenzoico (italian)
3-chloro-benzoic aci
3-chlorobenzoic
3-chlorobenzoicacid
3-Chlorbenzoesαure
m-Chlorbenzoesαure
3-Chloro-benzoic acid
3-Chlorobenzenecarboxylic acid
Benzoic acid,3-chloro-
3-chloro-Benzoic acid
m-Chlorobenzoic acid
m-chloro-benzoic aci
3-chlorobenzoic acid
展开更多英文名
性质描述: 白色单斜结晶。熔点158℃,加热升华,相对密度1.496(25/4℃)。易溶于醇和醚,溶于2850份冷水。
生产方法: (1)由2-氨基-5-氯苯甲酸脱氨而得将172份2-氨基-5-氯苯甲酸加到550份45%硫酸和600份异丙醇中。加热,在80℃滴加溶解100份亚硝酸钠于140份水的溶液。经6h,放出氮气,冷却加1500份水,过滤,得成品140份,收率为89%。(2)由间氯三氯甲苯水解而得将40份间氯三氯甲苯加到3100份1%氢氧化钠水溶液中,在97-99℃下反应1.5h而得,收率为98%。(3)由苯甲酸经氯化而得0.1mol苯甲酸和0.1mol氯化银加到100ml浓硫酸和15ml水的混合液中。冷却下加入已溶解7.8g氯的135ml的氯化碳中,搅拌3h,主要得到间氯苯甲酸,副产二氯苯甲酸。(4)间氯甲苯氧化法间氯甲苯在含有Co(OAC)2和NaBr的乙酸中,在95℃经液相催化氧化得间氯苯甲酸,收率为95%-96%。
用途: 医药、染料的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
C804553MACKLIN间氯苯甲酸99%38元/25g;   78元/100g;   349元/500g;   1267元/2.5kg;   咨询
储存:室温
状态:白色到灰白色粉末或晶体
C0132TCI3-Chlorobenzoic Acid>99.0%(GC)(T)275元/25G;   2405元/500G;   咨询

基本信息

纯度/分析方法>99.0%(GC)(T)
分子式/分子量C7H5ClO2 = 156.57
外观与形状(20℃)固体
Reaxys-RN907218
PubChem物质ID87565311
SDBS (AIST Spectral DB)1972
Merck Index (14)2123
MDL编号MFCD00002491

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 99.0 %
Purity(Neutralization titration)min. 99.0 %
Melting point155.0 to 159.0 ℃

物性(参考值)

熔点157 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#DG4975990
149955J&K3-Chlorobenzoic Acid99%95元/25G;   284元/100G;   1131元/500G;   咨询

基本信息

分子式C7H5ClO2
分子量156.57
熔点153-157
MDL编码MFCD00002491
Beilstein907218
Merck14,2123
EINECS 编号208-618-4

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSDG4975990
TSCA
A10876Alfa Aesar3-Chlorobenzoic Acid99%408元/25g;   1653元/100g;   3672元/500g;   咨询

应用
A Pseudomonas species which utilized 3-chlorobenzoic acid as a carbon source converted this compound to 3-hydroxybenzoic and 2, 5-dihydroxybenzoic acids. A methanogenic consortium able to use 3-chlorobenzoic acid as its sole energy and carbon source was enriched from anaerobic sewage sludge. A Pseudomonas putida strain 87 capable of assimilating 3-chlorobenzoic acid as a sole source of carbon and energy (3Cba+) was isolated. coupling of 3-chlorobenzoic acid with phenylboronic acid proceeds at room temperature using 0.5 % Pd and at 100?°C using 0.1 % Pd to provide the coupled product in 97 % yeild.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

基本信息

MDL
MFCD00002491

EINECS
208-618-4

分子式
C7H5ClO2

分子量
156.57

熔点
154-160°

沸点
274-276°

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Slioghtly soluble in water(0.45 g/L ).

Beilstein
907218

Merck
14,2123

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P280g-P305+P351+P338
Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
DG4975990

TSCA

C10866Alfa Aesar3-Chlorobenzoic Acid99+%541元/25g;   1501元/100g;   6946元/500g;   咨询

基本信息

Ref#
10866

MDL
2491

分子式
C7 H5 Cl O2

分子量
156.57

闪点
150

1112299USP3-Chlorobenzoic AcidUnited States Pharmacopeia (USP) Reference Standard10218.8元/25 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式ClC6H4CO2H
分子量156.57
Beilstein907218
MDL编号MFCD00002491
PubChem化学物质编号329749311
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp153-157 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringOC(=O)c1cccc(Cl)c1
InChI1S/C7H5ClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10)
InChI keyLULAYUGMBFYYEX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
C24604Sigma-Aldrich3-Chlorobenzoic AcidReagentPlus®, ≥99%303.95元/25 G;   614.4元/100 G;   咨询

产品说明

包装

25, 100 g in poly bottle

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF C24604.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息,请访问sigma.com/metlin。

法律信息

ReagentPlus is a registered trademark of sigma-aldrich Co. LLC

基本信息

线性分子式ClC6H4CO2H
分子量156.57
Beilstein907218
EC 号208-618-4
MDL编号MFCD00002491
PubChem化学物质编号24892490
NACRESNA.22

产品性质

产品线ReagentPlus®
质量水平100
测定≥99%
mp153-157 ℃ (lit.)
SMILES stringOC(=O)c1cccc(Cl)c1
InChI1S/C7H5ClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10)
InChI keyLULAYUGMBFYYEX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
V900680Sigma-Aldrich3-Chlorobenzoic AcidVetec, reagent grade, 98%209.71元/25 G;   432.77元/100 G;   咨询

产品说明

包装

25, 100 g in poly bottle

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

线性分子式ClC6H4CO2H
分子量156.57
Beilstein907218
EC 号208-618-4
MDL编号MFCD00002491
PubChem化学物质编号329830052

产品性质

等级reagent grade
产品线Vetec
测定98%
mp153-157 ℃ (lit.)
SMILES stringOC(=O)c1cccc(Cl)c1
InChI1S/C7H5ClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10)
InChI keyLULAYUGMBFYYEX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR1744Supelco3-Chlorobenzoic AcidPharmaceutical Secondary Standard; Certified Reference Material1940.49元/200 MG;   咨询

产品说明

一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
3-Chlorobenzoic acid may be used as a pharmaceutical reference standard for the determination of the analyte in bulk powders and pharmaceutical formulations by chromatography.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7967 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式ClC6H4CO2H
分子量156.57
Beilstein907218
EC 号208-618-4
MDL编号MFCD00002491
PubChem化学物质编号329823589

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 200 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp153-157 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1112299
储存温度2-30℃
SMILES stringOC(=O)c1cccc(Cl)c1
InChI1S/C7H5ClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10)
InChI keyLULAYUGMBFYYEX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
NIST2144m-Chlorobenzoic acidNIST® SRM® 21446113.14元/2 G;   咨询

产品说明

一般描述

This Standard Reference Material (SRM) is intended for use in the calibration and standardization of microchemical procedures for the determination of chlorine in organic materials. For more information, please refer to the COA and SDS.

SRM 2144_cert SRM 2144 _SDS

法律信息

NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology

基本信息

线性分子式ClC6H4CO2H
分子量156.57
Beilstein907218
MDL编号MFCD00002491
PubChem化学物质编号329818730
NACRESNA.24

产品性质

质量水平100
等级certified reference material
形式solid
包装pkg of 2 g
manufacturer/tradenameNIST®
mp153-157 ℃ (lit.)
application(s)pharmaceutical (small molecule)
SMILES stringOC(=O)c1cccc(Cl)c1
InChI1S/C7H5ClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10)
InChI keyLULAYUGMBFYYEX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
078545Fluorochem3-Chlorobenzoic Acid95%286元/25g;   440元/100g;   咨询

基本信息

CAS Number535-80-8
MDL NumberMFCD00002491
Melting Point157℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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