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CAS: 53-19-0
分子式: C14H10Cl4
分子量: 320.04
沸点: 65 °C甲醇
熔点: 76-78℃
中文名称: 
o,p'-滴滴滴
米托坦
氯苯二氯乙烷
英文名称: 
2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro-ethan
1,1-dichloro-2,2-bis(2,4'-dichlorophenyl)ethane
1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
1,1-dichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl)ethane
1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
2,2-bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane
2,4'-ddd
2,4'-dichlorodiphenyldichloroethane
2,4'-dichlorophenyldichlorethane
2-(2-chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane
2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloroethane
1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-benzen
cb 313
cb313
chloditan
chlodithane
1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-ethan
lysodren
mitotan
mitotane
nci-c04933
nsc 38721
nsc-38721
o,p'-ddd
o,p'-dichlorodiphenyldichloroethane
o,p'-tde
o,p-tde
1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2- dichloroethane
1,1-Dichloro-2-(2-chlorophenyl)-2-(4-chlorophenyl)ethane
ethane,2,2-dichloro-1-(2-chlorophenyl)-1-(4-chlorophenyl)-
1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane
1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane
(2,4'-Dichlorodiphenyl)dichloroethane
2,4'-DDD solution
1,1-Dichloro-2-(2-chlorophenyl)-2-(4-chlorophenyl)ethane solution
展开更多英文名
性质描述: 白色结晶。熔点76-78℃。溶于乙醇和四氯化碳。
生产方法: 由邻溴氯苯(见05820)经下述步骤制得。
用途: 抗肿瘤药,用于治疗肾上腺皮质癌。
推荐供应商
货号品牌产品名称规格包装、参考价格
767322MACKLIN2,4'-滴滴滴标准溶液10μg/mL in Cyclohexane577元/10ml;   咨询
储存:2-8°C, 避光
767138MACKLIN2,4'-滴滴滴标准溶液100μg/mL in Isooctane190元/1ml;   咨询
储存:2-8°C, 避光
767139MACKLIN2,4'-滴滴滴标准溶液200μg/mL in Isooctane230元/1ml;   咨询
储存:2-8°C, 避光
767140MACKLIN2,4'-滴滴滴标准溶液100μg/mL in Cyclohexane249元/1ml;   咨询
储存:2-8°C, 避光
767141MACKLIN2,4'-滴滴滴标准溶液100μg/mL in Hexane210元/1ml;   咨询
储存:2-8°C, 避光
767142MACKLIN2,4'-滴滴滴标准溶液1000μg/mL in Hexane260元/1ml;   咨询
储存:2-8°C, 避光
767143MACKLIN2,4'-滴滴滴标准溶液100μg/mL in Methanol260元/1ml;   咨询
储存:2-8°C, 避光
M833830MACKLIN米托坦98%140元/1g;   403元/5g;   1536元/25g;   咨询
储存:2~8°C
状态:无色晶体或白色结晶粉末
D796743MACKLIN2, 4'-滴滴滴标准溶液1000ug/ml in Purge and Trap Methanol410元/1ml;   咨询
储存:-20°C
D796742MACKLIN2, 4'-滴滴滴10mM in DMSO320元/1ml;   咨询
储存:-20°C
M3304TCIMitotane>98.0%(GC)490元/1G;   1490元/5G;   咨询

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C14H10Cl4 = 320.03
外观与形状(20℃)固体
Reaxys-RN2056007
Merck Index (14)6216
MDL编号MFCD00000850

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 98.0 %
Melting point76.0 to 80.0 ℃
Solubility in Methanolalmost transparency

物性(参考值)

熔点78 ℃
水溶性不溶
在水中的溶解度0.1 mg/l   25 ℃
溶解性(可溶于)乙醇,甲醇

安全信息

图形或危害标志
信号词危险
危险性说明H370 : 会损害器官。
H372 : 长期或反复接触会对器官造成损害。
H351 : 怀疑致癌。
H413 : 可能对水生生物造成长期持续有害影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P308+P311 : 如接触到或有疑虑:呼叫急救中心/医生。
P405 : 存放处须加锁。

相关法规

RTECS#KH7880000
R10189Alfa Aesar2,4'-DDD; o,p'-DDD Standard solution100ppm335元/1ml;   咨询

安全信息

危险等级
3

C10985Alfa AesarMitotane1319元/1g;   4837元/5g;   咨询

基本信息

Ref#
10985

分子式
C14H10Cl4

分子量
235.31

GHS危害和防范说明

GHS符号

Hazard Statements
H351
Suspected of causing cancer.

Precautionary Statements
P201 P280 P308+P313

35485Supelco2,4′-DDDPESTANAL®, analytical standard806.23元/250 MG;   咨询

产品说明

一般描述

2,4′-DDD is generally used to reduce the endogenous CORT neuropeptide, which might mask the total population of intracellular corticosteroid receptors in sparrows. It is an adrenal specific agent, which can find potent applications in the treatment of adrenocortical carcinoma (ACC).

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

PESTANAL is a registered trademark of sigma-aldrich International GmbH

基本信息

线性分子式(ClC6H4)2CHCHCl2
分子量320.04
Beilstein2056007
EC 号200-166-6
PubChem化学物质编号329755170
NACRESNA.24

产品性质

等级analytical standard
质量水平100
产品线PESTANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)agriculture
environmental
格式neat
SMILES stringClC(Cl)C(c1ccc(Cl)cc1)c2ccccc2Cl
InChI1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChI keyJWBOIMRXGHLCPP-UHFFFAOYSA-N
Gene Informationhuman ... CYP11A1(1583), CYP11B1(1584)

安全信息

象形图GHS08
警示用语:Warning
危险声明H351
预防措施声明P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
SML1885Sigma-AldrichMitotane≥98% (HPLC)689.87元/100 MG;   咨询

产品说明

包装

100 mg in glass bottle

生化/生理作用

Mitotane is a selective inhibitor of sterol-Oacyl-transferase 1 (SOAT1), also known as ACAT1, (acyl-coenzyme A cholesterol acyltransferase). Mitotane inhibition of SOAT1 in adrenocortical carcinoma cells decreased the formation of cholesteryl esters, which increased free cholesterol levels and caused endoplasmic reticulum (ER) stress, the unfolded protein response, and eventually apoptosis.

基本信息

经验(实验)分子式C14H10Cl4
分子量320.04
EC 号200-166-6
MDL编号MFCD00000850
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 20 mg/mL, clear
储存温度2-8℃
SMILES stringClC1=C(C(C(Cl)Cl)C2=CC=C(Cl)C=C2)C=CC=C1
InChI1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChI keyJWBOIMRXGHLCPP-UHFFFAOYSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H351
预防措施声明P280
危险分类Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1445007USPMitotaneUnited States Pharmacopeia (USP) Reference Standard3231.47元/500 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式(ClC6H4)2CHCHCl2
分子量320.04
Beilstein2056007
PubChem化学物质编号329750477
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringClC(Cl)C(c1ccc(Cl)cc1)c2ccccc2Cl
InChI1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChI keyJWBOIMRXGHLCPP-UHFFFAOYSA-N
Gene Informationhuman ... CYP11A1(1583), CYP11B1(1584)

安全信息

象形图GHS08
警示用语:Warning
危险声明H351
预防措施声明P280
危险分类Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
44012Supelco1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethanecertified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland1807.88元/50 mg;   咨询

产品说明

一般描述

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

法律信息

TraceCERT is a registered trademark of sigma-aldrich Co. LLC

基本信息

线性分子式(ClC6H4)2CHCHCl2
分子量320.04
Beilstein2056007
EC 号200-166-6
NACRESNA.24

产品性质

质量水平300
等级certified reference material
TraceCERT®
产品线TraceCERT®
保质期limited shelf life, expiry date on the label
格式neat
SMILES stringClC(Cl)C(c1ccc(Cl)cc1)c2ccccc2Cl
InChI1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChI keyJWBOIMRXGHLCPP-UHFFFAOYSA-N
Gene Informationhuman ... CYP11A1(1583), CYP11B1(1584)

安全信息

象形图GHS08
警示用语:Warning
危险声明H351
预防措施声明P280
危险分类Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
P-024NAccuStandardo,p'-DDD185元/10mg;   咨询
o,p'-DDDo,p'-DDD53-19-0
P-024SAccuStandardo,p'-DDD ,100 μg/mL in MeOH100 μg/mL in MeOH185元/1mL;   咨询
o,p'-DDDo,p'-DDD53-19-0100 µg/mL
P-024S-2AccuStandardo,p'-DDD ,2.0 ng/μL in Isooctane2.0 ng/μL in Isooctane185元/1mL;   咨询
o,p'-DDDo,p'-DDD53-19-02 ng/µL
P-024S-1AccuStandardo,p'-DDD ,200 ng/μL in Isooctane200 ng/μL in Isooctane185元/1mL;   咨询
o,p'-DDDo,p'-DDD53-19-0200 ng/µL
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