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CAS: 52809-07-1
分子式: C5H7N3O5
分子量: 189.12
熔点: 187-197℃
英文名称: 
quisqualic acid
l-quisqualic acid
用途: L-Quisqualic acid is a natural analog of glutamate that acts as an agonist at AMPA-selective and metabotropic glutamate receptors (EC50s = 170, 10, 40, and 29 nM at GluR-A, mGluR1, mGluR3, and mGluR5, respectively).
推荐供应商
货号品牌产品名称规格包装、参考价格
L912424MACKLINL-Quisqualic Acid98%2032元/5mg;   咨询
储存：-20°C，密闭，干燥
状态：白色粉末
Q2128Sigma-AldrichQuisqualic acidpowder1172.34元/1 MG;   4016.49元/5 MG;   5855.6元/10 MG;   15012.6元/25 MG;   咨询

产品说明

一般描述

Quisqualate/ Quisqualic acid is obtained from the fruits and seeds of Quisqualis chinensis. It is an agonist at two subsets of excitatory amino acid receptors metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores and, ionotropic receptors that directly control membrane channels. L-quisqualic acid is an agonist of the neurotransmitter L-glutamate.

应用

Quisqualic acid has been used to test ligand-gated receptors in spiral ganglion neurons.
Quisqualic acid has also been used as a group I metabotropic receptor agonist in neurons.

包装

1, 5 mg in glass bottle
10, 25 mg in poly bottle

生化/生理作用

Active enantiomer of quisqualic acid; excitatory amino acid at glutamate receptors.

基本信息

经验(实验)分子式C5H7N3O5
分子量189.13
Beilstein1078734
MDL编号MFCD00069337
PubChem化学物质编号24278004
NACRESNA.32

产品性质

质量水平200
形式powder
颜色 white to off-white
溶解性ethanol: <0.17 mg/mL
H2O: 0.5 mg/mL
0.1 M HCl: 1.4 mg/mL
1 M NH4OH: 20 mg/mL
organic solvents: insoluble
储存温度2-8℃
SMILES stringN[C@@H](CN1OC(=O)NC1=O)C(O)=O
InChI1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
InChI keyASNFTDCKZKHJSW-REOHCLBHSA-N
Gene Informationrat ... Gria1(50592), Grik1(29559), Grin2a(24409), Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
M02436FluorochemL-Quisqualic Acid>99%2090元/5mg;   3850元/10mg;   15664元/50mg;   咨询

基本信息

CAS Number52809-07-1
MDL NumberMFCD00069337

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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