|
|
| CAS: |
51940-44-4 |
| 分子弎 |
C14H17N5O3 |
| 分子野 |
303.33 |
| 中文名称: |
| 吡哌酷/td> |
| 8-乙基-5,8-二氢-5-?2-(1-哌嗪)-吡啶[2,3-D]并嘧?6-羧酸 |
| 吡卜酷/td> |
|
| 英文名称: |
| pyrido(2,3-d)pyrimidine-6-carboxylic acid, 5,8-dihydro-8-ethyl-5-oxo-2-(1-piper |
| 1489 rb |
| 5,8-dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-car boxy |
| acide ethyl-8 oxo-5 piperazinyl-2 dihydro-5,8 pyrido(2,3-d)pyrimidine-6 carbo |
| xylique |
| acido pipemidico |
| deblaston |
| dolcol |
| palin |
| pipedac |
| pipemid |
| pipemidic acid |
| piperamic acid |
| pipram |
| rb 1489 |
| uromidin |
|
| 性质描述: |
浅黄色结晶粉末。熔?51-255℃（分解）。易溶于冰醋酸，难溶于甲醇、丙酮、DMF，极难溶于水、乙醇、氯仿，不溶于苯，溶于稀碱或酸溶液。无臭，味苦、/td> |
| 生产方法: |
?,4-二氯嘧啶-5-羧酸乙酯与?乙氨基丙酸乙酯缩合环化为2-?5-羟基-7,8-二氢-8-乙基吡啶[2,3-d]嘧啶-6-羧酸酯。然后溴化后与哌嗪缩合、水解、中和而得吡哌酸、/td> |
| 用逓 |
该品是第二代喹诺酮类抗菌药物的代表，与萘啶酸相比抗菌谱较广，用于泌尿道感染及耳鼻喉科感染等、/td> |
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