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CAS: 51-52-5
分子式: C7H10N2OS
分子量: 170.22
熔点: 218-220 °C(lit.)
中文名称: 
丙硫氧嘧啶
丙基硫氧嘧啶
英文名称: 
6-propyl-2-thio-uraci
2,3-dihydro-6-propyl-2-thioxo-4(1h)-pyrimidinone
2,3-dihydro-6-propyl-2-thioxo-4(1h)pyrimidinone
2-mercapto-4-hydroxy-6-n-propylpyrimidine
2-mercapto-6-propyl-4-pyrimidone
2-mercapto-6-propylpyrimid-4-one
2-thio-4-oxo-6-propyl-1,3-pyrimidine
2-thio-6-propyl-1,3-pyrimidin-4-one
2,3-dihydro-6-propyl-2-thioxo-4(1h)-pyrimidinon
4-propyl-2-thiouracil
6-n-propyl-2-thiouracil
6-n-propylthiouracil
6-propil-tiouracile
6-propyl-2-thio-2,4(1h,3h)pyrimidinedione
6-propyl-2-thiouracil
6-propylthiouracil
6-thio-4-propyluracil
procasil
propacil
propilthiouracil
propycil
propyl thiouracil
propyl-thiorist
propyl-thiorit
propyl-thyracil
propylthiorit
propylthiouracil
propythiouracil
prothiucil
prothiurone
prothycil
prothyran
protiural
ptu (thyreostatic)
thiuragyl
thyreostat ii
4-hydroxy-2-mercapto-6-propylpyrimidine
展开更多英文名
用途: 抗甲状腺药。
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货号品牌产品名称规格包装、参考价格
P815829MACKLIN6-正丙基-2-硫代尿嘧啶分析对照品, ≥99%(GC)381元/250mg;   咨询
储存：室温
P815828MACKLIN6-正丙基-2-硫代尿嘧啶98%35元/5g;   87元/25g;   239元/100g;   1048元/500g;   4272元/2.5kg;   咨询
储存：室温
P794500MACKLIN6-正丙基-2-硫代尿嘧啶10mM in DMSO131元/1ml;   咨询
储存：-20°C
P0533TCI6-Propyl-2-thiouracil>99.0%(T)190元/25G;   咨询

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C7H10N2OS = 170.23
外观与形状(20℃)固体
应避免的情况光
Reaxys-RN130039
PubChem物质ID87574714
SDBS (AIST Spectral DB)1384
Merck Index (14)7869
MDL编号MFCD00006041

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Argentometric Titration)min. 99.0 %
Melting point218.0 to 221.0 ℃
Solubility in 1mol/L NaOHalmost transparency

物性(参考值)

熔点219 ℃
水溶性实际上不溶
在水中的溶解度1.2 g/l   25 ℃
溶解性(微溶于)乙醇,丙酮
溶解性(不溶于)苯,氯仿,乙醚

安全信息

图形或危害标志
信号词危险
危险性说明H302 : 吞咽有害。
H361 : 怀疑对生育能力或胎儿造成伤害。
H372 : 长期或反复接触会对器官造成损害。
H351 : 怀疑致癌。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P308 + P313 : 如接触到或有疑虑：求医/就诊。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#YR1400000
254393J&K6-Propyl-2-thiouracil99%60元/5G;   213元/25G;   701元/100G;   咨询

基本信息

分子式C7H10N2OS
分子量170.23
熔点218-220
闪点300
MDL编码MFCD00006041
Beilstein130039
EINECS 编号200-103-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
H351
防范说明P281
WGK3
RTECSYR1400000
TSCA是
C12131Alfa Aesar6-Propyl-2-thiouracil98%2442元/25g;   8513元/100g;   咨询

基本信息

Ref#
12131

分子式
C7H10N2OS

分子量
98.96

GHS危害和防范说明

Hazard Statements
H351 H302 H361d H362

Precautionary Statements
P280 P301+P330+P331 P312 P264 P201 P263

P3700000PropylthiouracilEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 30 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C7H10N2OS
分子量170.23
Beilstein130039
MDL编号MFCD00006041
PubChem化学物质编号329820187
NACRESNA.24

产品性质

等级pharmaceutical primary standard
描述enzyme inhibitor
manufacturer/tradenameEDQM
mp218-220 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCCC1=CC(=O)NC(=S)N1
InChI1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI keyKNAHARQHSZJURB-UHFFFAOYSA-N
Gene Informationhuman ... DIO1(1733), TPO(7173)

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H302 - H351
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
P3755Sigma-Aldrich6-Propyl-2-thiouracilenzyme inhibitor663.51元/10 G;   1033.89元/25 G;   3133.68元/100 G;   咨询

产品说明

一般描述

6-丙基-2-硫尿嘧啶或6-n-丙基硫尿嘧啶(PROP，或丙硫氧嘧啶PTU)是一种带苦味物质。

应用

6-丙基-2-硫尿嘧啶(PROP)已用于浸渍尝味片，用于研究限定人样品组中PROP品尝员的感官性状评价状态。 它已被用作筛选试剂，用于通过标签量值(labeled magnitude scale，LMS)测试味觉强度。
6-丙基-2-硫氧嘧啶是一种甲状腺抑制剂(甲状腺激素)，可作为毛细管电泳、高效液相色谱(HPLC) 或气相色谱等甲状腺药物分离检测技术中的标准物质。

包装

10, 25, 100 g in glass bottle

生化/生理作用

6-丙基-2-硫氧嘧啶(6-PTU)是D1碘甲状腺原氨酸脱碘酶的潜在抑制剂，参与了碘甲状腺原氨酸的脱碘作用。它是碘甲状腺原氨酸底物的非竞争性抑制剂。。

基本信息

经验(实验)分子式C7H10N2OS
分子量170.23
Beilstein130039
EC 号200-103-2
MDL编号MFCD00006041
PubChem化学物质编号24898446

产品性质

质量水平200
描述enzyme inhibitor
测定≥99% (HPLC)
形式powder
mp218-220 ℃ (lit.)
溶解性10% NH3: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES stringCCCC1=CC(=O)NC(=S)N1
InChI1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI keyKNAHARQHSZJURB-UHFFFAOYSA-N
Gene Informationhuman ... DIO1(1733), TPO(7173)

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H302 - H351
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
46698Supelco6-Propyl-2-thiouracilVETRANAL®, analytical standard524.29元/250 MG;   咨询

产品说明

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C7H10N2OS
分子量170.23
Beilstein130039
EC 号200-103-2
MDL编号MFCD00006041
PubChem化学物质编号329756620
NACRESNA.24

产品性质

质量水平200
等级analytical standard
描述enzyme inhibitor
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp218-220 ℃ (lit.)
application(s)clinical testing
格式neat
SMILES stringCCCC1=CC(=O)NC(=S)N1
InChI1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI keyKNAHARQHSZJURB-UHFFFAOYSA-N
Gene Informationhuman ... DIO1(1733), TPO(7173)

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H302 - H351
预防措施声明P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
8.22137Sigma-Aldrich4-Propyl-2-thiouracilfor synthesis414.38元/25 G;   905.83元/100 G;   咨询

产品说明

分析说明

Assay (HPLC, area%): ≥ 98.0 % (a/a)
Melting range (lower value): ≥ 216 °C
Melting range (upper value): ≤ 220 °C
Identity (IR): passes test

基本信息

经验(实验)分子式C7H10N2OS
分子量170.23
MDL编号MFCD00006041
EC索引号200-103-2

产品性质

质量水平200
测定≥98.0% (HPLC)
效能1250 mg/kg LD50, oral (Rat)
pH值(酸碱度)6-7.5 (20 ℃, 5 g/L in H2O, slurry)
mp216-220 ℃
转变温度flash point 300 ℃
溶解性 1.1 g/L
堆积密度159 kg/m3
储存温度2-30℃
InChI1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI keyKNAHARQHSZJURB-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H302 - H351
预防措施声明P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR2609SupelcoPropylthiouracilPharmaceutical Secondary Standard; Certified Reference Material2295.35元/500 MG;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC6192 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C7H10N2OS
分子量170.23
Beilstein130039
MDL编号MFCD00006041

产品性质

等级certified reference material
pharmaceutical secondary standard
描述enzyme inhibitor
形式solid
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
mp218-220 ℃ (lit.)
药典可追溯性traceable to PhEur P3700000
traceable to USP 1578000
储存温度2-30℃
SMILES stringCCCC1=CC(=O)NC(=S)N1
InChI1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI keyKNAHARQHSZJURB-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H302 - H351
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1578000USPPropylthiouracilUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C7H10N2OS
分子量170.23
Beilstein130039
MDL编号MFCD00006041
PubChem化学物质编号329750853
NACRESNA.24

产品性质

等级pharmaceutical primary standard
描述enzyme inhibitor
manufacturer/tradenameUSP
mp218-220 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCCCC1=CC(=O)NC(=S)N1
InChI1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI keyKNAHARQHSZJURB-UHFFFAOYSA-N
Gene Informationhuman ... DIO1(1733), TPO(7173)

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H302 - H351
预防措施声明P280 - P301 + P312 + P330
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
463632Fluorochem6-Propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one95%220元/1g;   286元/25g;   814元/100g;   咨询

基本信息

CAS Number51-52-5
MDL NumberMFCD00006041

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H351: Suspected of causing cancer ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P281: Use personal protective equipment as required.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9
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