| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| F838234 | MACKLIN | 非诺贝特 | 99%, powder | 35元/5g; 87元/25g; 306元/100g; 1385元/500g; | 咨询 |
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| F793151 | MACKLIN | 非诺贝特 | 10mM in DMSO | 341元/1ml; | 咨询 |
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| F0674 | TCI | Fenofibrate | >98.0%(GC) | 350元/5G; 990元/25G; 2390元/100G; | 咨询 |
基本信息 | 纯度/分析方法 | >98.0%(GC) | | 分子式/分子量 | C20H21ClO4 = 360.83 | | 外观与形状(20℃) | 固体 | | Reaxys-RN | 2062462 | | PubChem物质ID | 135726990 | | Merck Index (14) | 3978 | | MDL编号 | MFCD00133314 |
技术规格 | Appearance | White to Almost white powder to crystal | | Purity(GC) | min. 98.0 % | | Melting point | 79.0 to 83.0 ℃ |
物性(参考值) | 熔点 | 81 ℃ | | 水溶性 | 不溶 | | 溶解性(可溶于) | 丙酮,乙醚 | | 溶解性(微溶于) | 乙醇,甲醇 |
相关法规 |
| 316179 | J&K | Fenofibrate | 99%, 是PPARα激动剂, EC50为30 μM | 323元/5G; 941元/25G; | 咨询 |
基本信息 | 分子式 | C20H21ClO4 | | 分子量 | 360.83 | | MDL编码 | MFCD00133314 | | EINECS 编号 | 256-376-3 |
产品描述 Fenofibrate 是一种Fibrate类化合物，是纤维酸衍生物。 靶点（IC50 & Targe） CYP2B6,0.7μM CYP2C,EC50:2.39±0.4μM CYP2C19,0.2μM PPARα,30μM 参考文献 [1] Latruffe N, et al. Biochimie, 1997, 79(2-3):81-94. 安全信息 | 防范说明 | P262 | | WGK | 3 | | RTECS | UA2453400 |
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| C46178 | Alfa Aesar | Fenofibrate | 98% | 1007元/5g; 3345元/25g; 11863元/100g; | 咨询 |
基本信息 Ref#
46178 分子式
C20H21ClO4 分子量
316.38 GHS危害和防范说明 GHS符号
 Hazard Statements
H373 H413 Precautionary Statements
P260 P314 P273 P501 |
| F0048000 | | Fenofibrate | European Pharmacopoeia (EP) Reference Standard | 2199.9元/ ; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. 包装 Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. 注意 Please find SDS provided by EDQM here.. 其他说明 Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C20H21ClO4 | | 分子量 | 360.83 | | MDL编号 | MFCD00133314 | | PubChem化学物质编号 | 329799624 | | NACRES | NA.24 |
产品性质 | 质量水平 | 100 | | 等级 | pharmaceutical primary standard | | manufacturer/tradename | EDQM | | technique(s) | HPLC: suitable
gas chromatography (GC): suitable | | application(s) | pharmaceutical | | 格式 | neat | | SMILES string | CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 | | InChI | 1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3 | | InChI key | YMTINGFKWWXKFG-UHFFFAOYSA-N | | Gene Information | human ... PPARA(5465) |
安全信息 | 危险声明 | H412 | | 预防措施声明 | P273 - P501 | | 危险分类 | Aquatic Chronic 3 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| F6020 | Sigma-Aldrich | Fenofibrate | ≥99%, powder | 708.74元/5 G; 2060.83元/25 G; 5007.85元/100 G; | 咨询 |
产品说明 应用 非诺贝特已被用于：
- 研究其对血浆脂质、肝脏表型和基因表达的影响
- 研究其对胸主动脉内皮依赖性血管舒张的影响
- 给予 NASH 敲入小鼠以及高脂肪饮食 (HFD) 以研究其效果
生化/生理作用 非诺贝特通过减少胆固醇酯转运蛋白的表达增加高密度脂蛋白水平。用于治疗血液中胆固醇水平升高条件体内脂质水平异常以及高甘油三酯血症。非诺贝特是一种调脂药物和增殖物激活受体-α (PPARα) 介导其操作。降低血浆纤维蛋白原和 C 反应蛋白水平。非诺贝特可改善血流介导的血管扩张，降低动脉粥样硬化的风险。已知非诺贝特也可降低尿酸水平。 特点和优势 该化合物出现在《受体分类和信号转导手册》的 核受体 (PPAR) 页。要浏览其他手册页， 单击此处 。
该化合物由 Abbott 开发。如需浏览其他制药公司开发的化合物和批准的药物/候选药物列表，请点击此处。 基本信息 | 经验(实验)分子式 | C20H21ClO4 | | 分子量 | 360.83 | | EC 号 | 256-376-3 | | MDL编号 | MFCD00133314 | | PubChem化学物质编号 | 24278015 | | NACRES | NA.77 |
产品性质 | 质量水平 | 100 | | 测定 | ≥99% | | 形式 | powder | | 颜色 | off-white | | 创始人 | Abbott | | 储存温度 | room temp | | SMILES string | CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 | | InChI | 1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3 | | InChI key | YMTINGFKWWXKFG-UHFFFAOYSA-N | | Gene Information | human ... PPARA(5465) |
安全信息 | 危险声明 | H412 | | 预防措施声明 | P273 - P501 | | 危险分类 | Aquatic Chronic 3 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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| PHR1246 | Supelco | Fenofibrate | Pharmaceutical Secondary Standard; Certified Reference Material | 1631.37元/500 MG; | 咨询 |
产品说明 一般描述 Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Fenofibrate is a third-generation fibric acid derivative which is widely employed for the treatment of atherogenic dyslipidemia, hypertriglyceridemia, mixed dyslipidemia and hypercholesterolemia. 应用 These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Fenofibrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography and spectrophotometry techniques. 分析说明 These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. 其他说明 This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. 附注 To see an example of a Certificate of Analysis for this material enter LRAC0257 in the slot below. This is an example certificate only and may not be the lot that you receive. 基本信息 | 经验(实验)分子式 | C20H21ClO4 | | 分子量 | 360.83 | | EC 号 | 256-376-3 | | MDL编号 | MFCD00133314 | | PubChem化学物质编号 | 329823250 | | NACRES | NA.24 |
产品性质 | 质量水平 | 300 | | 等级 | certified reference material
pharmaceutical secondary standard | | CofA | current certificate can be downloaded | | technique(s) | HPLC: suitable
gas chromatography (GC): suitable | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 药典可追溯性 | traceable to PhEur F0048000
traceable to USP 1269447 | | 储存温度 | 2-8℃ | | SMILES string | CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 | | InChI | 1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3 | | InChI key | YMTINGFKWWXKFG-UHFFFAOYSA-N | | Gene Information | human ... PPARA(5465) |
安全信息 | 危险声明 | H412 | | 预防措施声明 | P273 - P501 | | 危险分类 | Aquatic Chronic 3 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 1269447 | USP | Fenofibrate | United States Pharmacopeia (USP) Reference Standard | 3231.47元/200 MG; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. 分析说明 These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. 其他说明 USP issued SDS can be found here.
Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C20H21ClO4 | | 分子量 | 360.83 | | MDL编号 | MFCD00133314 | | PubChem化学物质编号 | 329749836 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | USP | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | SMILES string | CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 | | InChI | 1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3 | | InChI key | YMTINGFKWWXKFG-UHFFFAOYSA-N | | Gene Information | human ... PPARA(5465) |
安全信息 | 危险声明 | H412 | | 预防措施声明 | P273 - P501 | | 危险分类 | Aquatic Chronic 3 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 973617 | Amethyst | Fenofibrate | 98%, 试剂级 | 293元/5G; 901元/25G; 2384元/100G; | 咨询 |
基本信息 | 分子式 | C20H21ClO4 | | 分子量 | 360.83 | | MDL编码 | MFCD00133314 | | EINECS 编号 | 256-376-3 |
安全信息 | 防范说明 | P262 | | WGK | 3 | | RTECS | UA2453400 |
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| 223141 | Fluorochem | Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate | 95% | 726元/5g; 2244元/25g; 7282元/100g; | 咨询 |
基本信息 | CAS Number | 49562-28-9 | | MDL Number | MFCD00133314 |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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