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CAS: 4906-68-7
分子式: C13H9BrO3
分子量: 293.11
中文名称: 
aldo-keto reductase family 1 member c1 inhibitor, 5-pbsa, 3-bromo-5-phenylsalicylic acid, 20α-hydroxysteroid dehydrogenase inhibitor, 5-pbsa
英文名称: 
akr1c1 inhibitor, 5-pbsa-cas 4906-68-7-calbiochem
推荐供应商
货号品牌产品名称规格包装、参考价格
A937795MACKLIN3-bromo-5-phenylsalicylic acid≥98%338元/10mg;   629元/25mg;   808元/50mg;   1442元/100mg;   咨询
储存:2-8°C,密封,干燥
状态:固体
A793505MACKLIN3-bromo-5-phenylsalicylic acid10mM in DMSO408元/1ml;   咨询
储存:-20°C
123850Sigma-AldrichAKR1C1 Inhibitor, 5-PBSA-CAS 4906-68-7-CalbiochemThe AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1.3543.57元/25 MG;   咨询

产品说明

一般描述

A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki = 4 nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki = 0.087, 4.2 and 18.2 µM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50 = 460 nM in AKR1C1 overexpressing BAECs).

包装

25 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

El-Kabbani, O., et al. 2011. J. Steroid Biochem. Mol. Biol.125, 105.
El-Kabbani, O., et al. 2009. J. Med. Chem.52, 3259.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C13H9BrO3
分子量293.11
MDL编号MFCD16495825

产品性质

质量水平100
测定≥94% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性DMSO: 50 mg/mL
运输wet ice
储存温度2-8℃
SMILES stringOC1=C(C(O)=O)C=C(C2=CC=CC=C2)C=C1Br
InChI1S/C13H9BrO3/c14-11-7-9(8-4-2-1-3-5-8)6-10(12(11)15)13(16)17/h1-7,15H,(H,16,17)
InChI keyXVZSXNULHSIRCQ-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
547742Fluorochem5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid95+%4026元/1g;   咨询

基本信息

CAS Number4906-68-7
MDL NumberMFCD18378258
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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