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CAS: 460-00-4
分子式: C6H4BrF
分子量: 175.01
沸点: 150℃
熔点: -8-155℃
中文名称: 
1-溴-4-氟苯
对氟溴苯
对溴氟苯
4-溴氟代苯
4-溴氟苯
1-氟-4-溴苯
英文名称: 
1-Bromo-4-fluorobenzene
1-fluoro-4-bromobenzene
4-bromofluorobenzene
4-fluoro-1-bromobenzene
4-fluorobromobenzene
4-fluorophenyl bromide
1-bromo-4-fluoro-benzen
nsc 10268
p-bromofluorobenzene
1-Bromo-4-fluorobenzene solution
p-fluorobromobenzene
p-fluorophenyl bromide
BFB
1-bromo-4-fluoro-benzene
Benzene,1-bromo-4-fluoro-
4-Bromfluorbenzol
4-Fluorbrombenzol
1-Brom-4-fluorbenzol
展开更多英文名
性质描述: 无色透明液体。熔点-8℃,凝固点-17.4℃,相对密度(20/4℃)1.4964,折光率1.5604,沸点153.5℃。不溶于水,溶于乙醇、乙醚。
生产方法: 将干燥的溴素滴加入沸腾的氟苯和吡啶的混合物中,反应产生的溴化氢用水吸收。然后继续加热2h。冷却,加入氢氧化钠溶液,用乙醚萃取,萃取液加无水碳酸钾干燥,分馏。75-90℃的馏分为未反应的氟苯,148-154℃的馏分为对溴氟苯。产率约49%。
用途: 有机合成中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
B796407MACKLIN对氟溴苯1000μg/ml in Methanol168元/1.2ml;   咨询
储存:室温
B802508MACKLIN对氟溴苯98%34元/25g;   62元/100g;   220元/500g;   945元/2.5kg;   3024元/10kg;   咨询
储存:2~8°C
状态:无色液体
折射率:n20/D 1.527(lit.)
B0884TCI4-Bromofluorobenzene>98.0%(GC)135元/25G;   505元/100G;   660元/500G;   咨询

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C6H4BrF = 175.00
外观与形状(20℃)液体
Reaxys-RN774102
PubChem物质ID87563858
SDBS (AIST Spectral DB)4185
MDL编号MFCD00000342

技术规格

AppearanceColorless to Light yellow clear liquid
Purity(GC)min. 98.0 %

物性(参考值)

沸点153 ℃
闪点56 ℃
比重1.60
折射率1.53
水溶性不溶

安全信息

图形或危害标志
信号词警告
危险性说明H303 : 吞咽可能有害。
H316 : 造成轻微皮肤刺激。
H319 : 造成严重眼刺激。
H226 : 易燃液体和蒸气。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P240 : 容器和装载设备接地/等势联接。
P210 : 远离热源/火花/明火/热表面。禁止吸烟。
P233 : 保持容器密闭。
P243 : 采取防止静电放电的措施。
P241 : 使用防爆的电气/通风/照明设备。
P242 : 只能使用不产生火花的工具。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P370 + P378 : 火灾时:使用干砂、干粉或抗醇泡沫灭火。
P312 : 如感觉不适,呼叫急救中心/医生。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P403 + P235 : 存放在通风良好的地方。保持低温。

相关法规

RTECS#CY9033750

运输信息

UN编号UN1993
类别3
包装类别 III
监管条件代码(*)
187086J&K1-Bromo-4-fluorobenzene99%143元/25ML;   395元/100ML;   981元/500ML;   咨询

基本信息

分子式C6H4BrF
分子量175.00
熔点-16
沸点150
闪点53
密度1.593
折光率(n20D)1.5260-1.5290
MDL编码MFCD00000342
Beilstein774102
EINECS 编号207-300-2

安全信息

图形或危害标志
提示语Warning
危险说明H226
H315
H319
H332
H335
防范说明P261
P305+P351+P338
UN号码1993
危险分类3
包装等级III
WGK3
RTECSCY9033750
TSCA
A11630Alfa Aesar1-Bromo-4-fluorobenzene99%652元/100g;   1284元/500g;   5210元/2500g;   咨询

应用
1-Bromo-4-fluorobenzene is used as an intermediate in the synthesis of atypical antipsychotic agents.

备注
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

基本信息

MDL
MFCD00000342

EINECS
207-300-2

分子式
C6H4BrF

分子量
175.01

熔点
-16°

沸点
151-153°

闪点
60°(140°F)

密度
1.604

折射率
1.5270

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Soluble in water(0.14g/L).

Beilstein
774102

GHS危害和防范说明

GHS符号

Hazard Statements
H226-H313-H332-H319
Flammable liquid and vapour.May be harmful in contact with skin.Harmful if inhaled.Causes serious eye irritation.

Precautionary Statements
P261-P305+P351+P338
Avoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险等级
3

包装组
III

危险类别
10-20-36
Flammable.Harmful by inhalation.Irritating to eyes.

安全等级
26
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

欧盟危险品标志

RTECS
CY9033750

TSCA

C10701Alfa Aesar4-Bromofluorobenzene99%504元/10ml;   2539元/100ml;   12240元/500ml;   咨询

基本信息

Ref#
10701

MDL
342

分子式
C6 H4 Br F

分子量
175

闪点
53

密度
1593

安全信息

危险等级
3

包装组
III

B67201Sigma-Aldrich1-Bromo-4-fluorobenzene99%265.55元/25 G;   471.4元/100 G;   960.33元/500 G;   咨询

基本信息

线性分子式BrC6H4F
分子量175.00
Beilstein774102
EC 号207-300-2
MDL编号MFCD00000342
PubChem化学物质编号24891932
NACRESNA.22

产品性质

质量水平100
测定99%
折射率n20/D 1.527 (lit.)
bp150 ℃ (lit.)
mp−16 ℃ (lit.)
密度1.593 g/mL at 25 ℃ (lit.)
SMILES stringFc1ccc(Br)cc1
InChI1S/C6H4BrF/c7-5-1-3-6(8)4-2-5/h1-4H
InChI keyAITNMTXHTIIIBB-UHFFFAOYSA-N

安全信息

象形图GHS02GHS07
警示用语:Warning
危险声明H226 - H332
预防措施声明P210 - P304 + P340 + P312
危险分类Acute Tox. 4 Inhalation - Flam. Liq. 3
储存分类代码3 - Flammable liquids
WGKWGK 1
闪点(F)127.4 °F - closed cup
闪点(C)53 ℃ - closed cup
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
AS-E0233AccuStandardp-Bromofluorobenzene ,0.15 mg/mL in MeOH0.15 mg/mL in MeOH494元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-40.15 mg/mL
CLP-004AccuStandardp-Bromofluorobenzene,25 μg/mL in MeOH25 μg/mL in MeOH154元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-425 µg/mL
CLP-004-100X-PAKAccuStandardp-Bromofluorobenzene,2.5 mg/mL in MeOH2.5 mg/mL in MeOH760元/5×1mL;   咨询
CLP-004-10X-PAKAccuStandardp-Bromofluorobenzene,250 μg/mL in Methanol250 μg/mL in Methanol760元/5×1mL;   咨询
CLP-004-1000XAccuStandardp-Bromofluorobenzene,25 mg/mL in MeOH25 mg/mL in MeOH309元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-425 µg/mL
CLP-004-10XAccuStandardp-Bromofluorobenzene,250 μg/mL in Methanol250 μg/mL in Methanol154元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-4250 µg/mL
CLP-004-80X-PAKAccuStandardp-Bromofluorobenzene,2.0 mg/mL in MeOH2.0 mg/mL in MeOH760元/5×1mL;   咨询
CLP-004-80XAccuStandardp-Bromofluorobenzene,2.0 mg/mL in MeOH2.0 mg/mL in MeOH154元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-425 µg/mL
CLP-004-PAKAccuStandardp-Bromofluorobenzene,25 μg/mL in MeOH25 μg/mL in MeOH760元/5×1mL;   咨询
CLP-004-100XAccuStandardp-Bromofluorobenzene,2.5 mg/mL in MeOH2.5 mg/mL in MeOH154元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-425 µg/mL
M-624-SS-03-10XAccuStandardp-Bromofluorobenzene ,2.0 mg/mL in MeOH2.0 mg/mL in MeOH154元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-425 µg/mL
M-624-SS-03AccuStandardp-Bromofluorobenzene ,0.2 mg/mL in MeOH0.2 mg/mL in MeOH154元/1mL;   咨询
p-Bromofluorobenzene对溴氟苯460-00-425 µg/mL
001225Fluorochem1-Bromo-4-fluorobenzene98%550元/100g;   1320元/500g;   咨询

基本信息

CAS Number460-00-4
MDL NumberMFCD00000342
Boiling Point152-155℃
Melting Point-18 to -16℃
Density1.604

安全信息

图形或危害标志
危险性说明 H226: Flammable liquid and vapour.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P210: Keep away from – No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof ./ equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P370 + P378: In case of fire: Use sand, CO2 or extinguishing powder for extinction.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P403 + P235: Store in a well-ventilated place. Keep cool.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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