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CAS: 41964-07-2
分子式: C11H10N2O2
分子量: 202.21
英文名称: 
tolimidone
用途: MLR-1023是Lyn kinase 激活剂,也是一种新型的insulin receptor 增强剂,在具有2型糖尿病的动物模型中使得葡萄糖稳态快速起效、并持久改善。
推荐供应商
货号品牌产品名称规格包装、参考价格
M872508MACKLINMLR-102399%370元/5mg;   1205元/25mg;   咨询
储存:-20℃
状态:白色到黄色固体
SML0371Sigma-AldrichMLR-1023≥98% (HPLC)881.29元/5 MG;   3573.74元/25 MG;   咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

MLR-1023 has a therapeutic potential to treat type 2 diabetes.
MLR-1023 is a potent, orally active, allosteric activator of the non-receptor Src-related Lyn kinase that produces lasting glucose lowering, reduces HbA1c levels, and preserves pancreatic β-cells in db/db mice. MLR-1023 increased insulin receptor sensitivity. MLR-1023 (Tolimidone) is antiulcer agent.

特点和优势

This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式C11H10N2O2
分子量202.21
MDL编号MFCD00866900
PubChem化学物质编号329825372
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 15 mg/mL (clear solution)
储存温度room temp
SMILES stringCc1cccc(OC2=CNC(=O)N=C2)c1
InChI1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)
InChI keyHJQILFPVRNHTIG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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