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CAS: 41179-33-3
分子式: C22H20FNO2
分子量: 349.4
英文名称: 
mk2a inhibitor-cas 41179-33-3-calbiochem
mitogen-activated protein kinase-activated protein kinase 2a inhibitor, 4-(2'-fluorobiphenyl-4-yl)-n-(4-hydroxyphenyl)-butyramide, cmpd1, mapkapk2a inhibitor
推荐供应商
货号品牌产品名称规格包装、参考价格
C937462MACKLIN4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide≥99%747元/5mg;   1280元/10mg;   4050元/50mg;   咨询
储存:2-8°C,密封,干燥
状态:固体
475863Sigma-AldrichMK2a Inhibitor-CAS 41179-33-3-CalbiochemThe MK2a Inhibitor, also referenced under CAS 41179-33-3, controls the biological activity of MK2a. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicat3945.15元/5 MG;   咨询

产品说明

一般描述

A reversible p-amidophenolic compound that selectively inhibits the phosphorylation of MK2a (mitogen-activated protein kinase-activated protein kinase 2a; Kiapp = 330 nM) by p38α in a non-ATP-competitive manner. Does not block the kinase activity of p38α towards the other two known p38 substrates, MBP and ATF-2.
A non-ATP-competitive, reversible, selective inhibitor of p38α-mediated MK2a (mitogen-activated protein kinase-activated protein kinase 2a) phosphorylation (Kiapp = 330 nM). Does not inhibit p38α-mediated phosphorylation of the the other two known p38 substrates, MBP and ATF-2.

包装

5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Kiapp = 330 nM against mitogen-activated protein kinase-activated protein kinase 2a (MK2a)
Product does not compete with ATP.
Primary Target
Mk2α
Cell permeable: no
Reversible: yes

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Davidson, W., et al. 2004. Biochemistry43, 11658.
Lukas, S.M., et al. 2004. Biochemistry43, 9950.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C22H20FNO2
分子量349.40

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色pale yellow
溶解性DMSO: 5 mg/mL
ethanol: 5 mg/mL
运输ambient
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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