CAS 393514-24-4; bctc - �뵺�羺�ٷ��ַ

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CAS:

393514-24-4

分子式:

C₂₀H₂₅ClN₄O

分子量:

372.89

英文名称:

bctc

4-(3-chloro-2-pyridinyl)-n-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide

用途:

BCTC作用于前列腺癌 (PCa) DU145细胞，有效且特异性抑制瞬时受体阳离子通道M成员8(TRPM8)。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

B879195

MACKLIN

BCTC

97%

288元/10mg; 928元/50mg;

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储存：2-8℃
状态：白色到灰白色到米黄色粉末

B795205

MACKLIN

BCTC

10mM in DMSO

320元/1ml;

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储存：-20°C

SML0355

Sigma-Aldrich

BCTC

≥98% (HPLC)

1203.82元/5 MG; 3700.95元/25 MG;

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产品说明

应用

BCTC or (4-Tertbutylphenyl)-4-(3-chloropyridin-2-Yl) tetrahydropyrazine-1(2H)-carbox-amide has been used as transient receptor potential melastatin 8 (TRPM8) antagonist to study its effects on proliferation and cell viability.

包装

5, 25 mg in glass bottle

生化/生理作用

BCTC is a potent antagonist of the vanilloid receptor TRPV1. BCTC blocks capsaicin-induced contractions in a variety of smooth muscle tissues, including guinea pig ileum, bladder and trachea with no effects on capsaicin-sensitive, sensory neuron-mediated positive inotropy. The compound penetrates the CNS and has strong analgesic properties.

基本信息

经验(实验)分子式	C₂₀H₂₅ClN₄O
分子量	372.89
MDL编号	MFCD08690556
PubChem化学物质编号	329825357

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: >10 mg/mL
储存温度	room temp
SMILES string	CC(C)(C)c1ccc(NC(=O)N2CCN(CC2)c3ncccc3Cl)cc1
InChI	1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26)
InChI key	ROGUAPYLUCHQGK-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

468410

Fluorochem

BCTC

98%

2398元/10mg; 13134元/250mg; 32780元/1g;

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基本信息

CAS Number	393514-24-4
MDL Number	MFCD08690556

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