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CAS: 371980-98-2
分子式: C24H29Cl2NO · HCl
分子量: 454.86
英文名称: 
sb-612111 hydrochloride
(5S,7S)-7-[[4-(2,6-dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5h-benzocyclohepten-5-ol hydrochloride
用途: SB-612111 is a potent antagonist of the nociceptin receptor ORL-1. SB-612111 binds to ORL-1 with high affinity (Ki = 0.33 nM) but has very low affinity for classic opioid receptors. The compound SB-612111 antagonizes the anti-morphine effects of nociceptin and blocks nociceptin-induced thermal hyperalgesia.
推荐供应商
货号品牌产品名称规格包装、参考价格
S921012MACKLINSB-612111 hydrochloride≥98% (HPLC)1048元/5mg;   咨询
储存:−20°C
状态:固体
SML0571Sigma-AldrichSB-612111 hydrochloride≥98% (HPLC)1549.77元/5 MG;   6268.49元/25 MG;   咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

SB-612111 is a potent antagonist of the nociceptin receptor ORL-1. SB-612111 binds to ORL-1 with high affinity (Ki = 0.33 nM) but has very low affinity for classic opioid receptors. The compound SB-612111 antagonizes the anti-morphine effects of nociceptin and blocks nociceptin-induced thermal hyperalgesia.

特点和优势

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C24H29Cl2NO · HCl
分子量454.86
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 15 mg/mL, clear
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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