CAS 37178-37-3; l-dopa乙酯; l-dopa ethyl ester

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CAS:

37178-37-3

分子式:

C₁₁H₁₅NO₄

分子量:

225.24

沸点:

394.2 °C at 760 mmHg

中文名称:

l-dopa乙酯

l-多巴乙酯

3-羟基-l-酪氨酸乙酯

依替伏多巴

3,4-二羟基-l-苯丙氨酸乙酯

左旋多巴乙酯

英文名称:

l-dopa ethyl ester

3,4-dihydroxy-l-phenylalanine ethyl ester

l-dopa-et

tv-1203

o-ethyl-dopa

etilevodopa

levodopa ethyl ester

3-hydroxy-l-tyrosine ethyl ester

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

S920751

MACKLIN

左旋多巴乙酯

98%(HPLC)

1295元/5mg;

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储存：2-8°C
状态：浅黄色液体

SML0091

Sigma-Aldrich

L-Dopa ethyl ester

≥98% (HPLC)

1666.25元/5 MG; 5077.25元/25 MG;

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产品说明

应用

L-多巴乙酯已被用于研究哌隆定(PLG)对鱼藤酮诱导的帕金森病(PD)的保护作用。

包装

5, 25 mg in glass bottle

生化/生理作用

L-多巴乙酯(L-Dopa)是一种多巴胺替代药物。它被用作帕金森病(PD)的有效疗法。 L-Dopa 具有一些长期的副作用，例如运动功能下降。
L-多巴乙酯是左旋多巴的前药，具有更高的胃溶解性。该药在胃肠道中被非特异性酯酶迅速水解为左旋多巴。与标准左旋多巴-卡比多巴治疗相比，左旋多巴乙酯(依替伏多巴)-卡比多巴治疗耐受性好，但并未显示出更好的疗效。注射给药后，左旋多巴乙酯应具有明显的脑渗透能力。

特点和优势

该化合物出现在受体分类和信号转导手册的多巴胺和去甲肾上腺素代谢页。想要浏览手册的其他页面，请点击此处。

基本信息

经验(实验)分子式	C₁₁H₁₅NO₄
分子量	225.24
MDL编号	MFCD00871210
PubChem化学物质编号	329825151

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D +15 to +19°, c = 1 in methanol ([α]/D)
颜色	white to tan
溶解性	H₂O: ≥12 mg/mL at warmed to 60 ℃
储存温度	2-8℃
SMILES string	CCOC(=O)[C@@H](N)Cc1ccc(O)c(O)c1
InChI	1S/C11H15NO4/c1-2-16-11(15)8(12)5-7-3-4-9(13)10(14)6-7/h3-4,6,8,13-14H,2,5,12H2,1H3/t8-/m0/s1
InChI key	NULMGOSOSZBEQL-QMMMGPOBSA-N
Gene Information	human ... DRD3(1814)

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H319
预防措施声明	P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

535285

Fluorochem

(S)-ETHYL 2-AMINO-3-(3,4-DIHYDROXYPHENYL)PROPANOATE

95%

5324元/5mg; 15972元/25mg;

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基本信息

CAS Number	37178-37-3
MDL Number	MFCD00871210

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: . P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see . on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to local regulations.

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