CAS 361189-64-2; 1-羟基-3,6,9,12,15,18-六氧杂二十一烷-21-甲酸叔丁酯; tert-butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate

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货号

品牌

产品名称

规格

包装、参考价格

H904828

MACKLIN

羟基-六聚乙二醇-丙酸叔丁酯

96%

146元/250mg; 535元/1g; 2548元/5g;

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储存：-20℃，惰性气体，密封
状态：液体

2326485

J&K

Hydroxy-PEG6-t-butly ester

95%

703元/250MG; 2109元/1G;

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基本信息

分子式	C₁₉H₃₈O₉
分子量	410.50
密度	1.068
存储条件	Freezer -20℃

安全信息

WGK

902578

Sigma-Aldrich

Hydroxy-PEG6-t-butyl ester

≥95%

1375.45元/250 MG;

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产品说明

应用

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or roteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

其他说明

Synthesis and Molecular Recognition Studies of the HNK-1 Trisaccharide and Related Oligosaccharides. The Specificity of Monoclonal Anti-HNK-1 Antibodies as Assessed by Surface Plasmon Resonance and STD NMR

Maleimide-oligo(ethylene glycol) Derivatives of Camptothecin as Albumin-Binding Prodrugs: Synthesis and Antitumor Efficacy

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C₁₉H₃₈O₉
分子量	410.50

产品性质

测定	≥95%
形式	liquid
reaction suitability	reagent type: cross-linking reagent
折射率	n/D 1.454
密度	1.068
储存温度	−20℃
SMILES string	O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable