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CAS: 3424-98-4
分子式: C10H14N2O5
分子量: 242.23
中文名称: 
1-(2-deoxy-β-l-erythro-pentofuranosyl)-5-methyl-2,4(1h,3h)-pyrimidinedione
2′-deoxy-l-thymidine
β-l-thymidine
英文名称: 
telbivudine
epavudine
sebivo
nv 02b
l-thymidine
推荐供应商
货号品牌产品名称规格包装、参考价格
T796821MACKLIN替比夫定-d395%, 95atom%D4488元/1mg;   咨询
储存:-20°C
T864685MACKLINTelbivudine≥98%30元/5mg;   46元/25mg;   118元/100mg;   255元/500mg;   466元/1g;   1666元/5g;   咨询
储存:2-8°C
状态:白色到灰白色固体
T796822MACKLINTelbivudine10mM in DMSO308元/1ml;   咨询
储存:-20°C
814159J&K2'-Deoxy-L-thymidine98%2009元/10mg;   咨询

基本信息

分子式C10H14N2O5
分子量242.23
熔点188-190
MDL编码MFCD02683612
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H302
防范说明P262
WGK3
RTECSUV9048500
C46455Alfa AesarL-Thymidine3647元/1g;   11476元/5g;   咨询

基本信息

Ref#
46455

分子式
C10H14N2O5

分子量
1579.58

GHS危害和防范说明

GHS符号

Hazard Statements
H302
Harmful if swallowed.

Precautionary Statements
P301+P330+P331 P312 P264

SML0293Sigma-AldrichTelbivudine≥98% (HPLC)1295.33元/5 MG;   6177.46元/25 MG;   咨询

产品说明

应用

Telbivudine has been used to explore the mechanisms of telbivudine (LdT) induced creatine kinase (CK) elevation.

包装

5, 25 mg in glass bottle

生化/生理作用

Telbivudine is a nucleoside analog that is widely used to treat hepatitis B virus (HBV) infection.
Telbivudine is a synthetic molecule containing β-L-configuration. Telbivudine improves the estimated glomerular filtration rate (eGFR) in response to chronic hepatitis B (CHB). It prevents perinatal transmission and enhances the hepatitis B e antigen (HBeAg) seroconversion. It is also known to cause side effects such as creatine kinase (CK) elevation and fatal rhabdomyolysis.

基本信息

经验(实验)分子式C10H14N2O5
分子量242.23
MDL编号MFCD02683612
PubChem化学物质编号329825300
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
旋光性[α]/D -15 to -22°, c = 1 in H2O
颜色 white to beige
溶解性H2O: 10 mg/mL (clear solution)
储存温度2-8℃
SMILES stringCC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O
InChI1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
InChI keyIQFYYKKMVGJFEH-CSMHCCOUSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
091804FluorochemL-Thymidine95%1012元/1g;   4554元/5g;   17072元/25g;   咨询

基本信息

CAS Number3424-98-4
MDL NumberMFCD02683612
Melting Point188-190℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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