[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 315-30-0
关键词:       仅模糊查询
CAS: 315-30-0
分子式: C5H4N4O
分子量: 136.11
熔点: 350℃
中文名称: 
4-羟基吡唑-(3,4-D)吡唑
别嘌醇
1H-吡唑(3,4-D)并嘧啶-4-醇
别嘌呤
别嘌呤醇
英文名称: 
lysuron
miniplanor
monarch
nektrohan
nsc-1390
remid
riball
suspendol
takanarumin
urbol
uricemil
uriprim
uripurinol
urobenyl
urosin
urtias 100
xanturat
zyloprim
zyloric
4-hydroxypyrazolo[3,4-d]pyrimidine
h-pyrazolo(3,4-d)pyrimidin-4-ol
1,5-dihydro-4h-pyrazolo(3,4-d)pyrimidin-4-one
1,5-dihydro-4h-pyrazolo(3,4-d)pyrimidine-4-one
1h-pyrazolo(3,4-d)pyrimidin-4-ol
4'-hydroxypyrazolol(3,4-d)pyrimidine
4-hydroxy-1h-pyrazolo(3,4-d)pyrimidine
4-hydroxy-3,4-pyrazolopyrimidine
4-hydroxypyrazolo(3,4-d)pyrimidine
4-hydroxypyrazolopyrimidine
4-hydroxypyrazolyl(3,4-d)pyrimidine
4h-pyrazolo(3,4-d)pyrimidin-4-one
4-d)pyrimidin-4-one, 1,5-dihydro-4h-pyrazolo(
4-d]pyrimidin-4-one, 1,5-dihydro-4h-pyrazolo[
adenock
al-100
allo-puren
allopur
allopurinol
allopurinol(i)
allozym
allural
aloral
alositol
aluline
anoprolin
anzief
apulonga
apurin
apurol
atisuril
bleminol
bloxanth
bw 56-158
bw 56158
caplenal
cellidrin
cosuric
dabrosin
dabroson
dura al
embarin
epidropal
epuric
foligan
geapur
gichtex
hamarin
hexanuret
hpp
ketanrift
ketobun-a
ledopur
lopurin
展开更多英文名
性质描述: 白色或类白色结晶状粉末。熔点383-384℃。溶于碱液,极微溶于水及一般有机溶剂,不溶于氯仿、乙醚。
生产方法: 将氰乙酸乙酯、原甲酸三乙酯、乙酐放在反应罐中回流反应4h,缩合得到α-乙氧次甲基氰乙酸乙酯:再将其溶解在乙醇中,加入水合肼,加热回流反应6h,得3-氨基-4-乙氧羰基吡唑;最后与甲酰胺一起加热回流反应8h,环合得到别嘌醇。用蒸馏水溶解,活性炭脱色,得精制的别嘌醇。对氰乙酸乙酯计,总收率41.8%
用途: 抗痛风药。适用于原发性或继发性血清尿酸增多的各种疾病,如痛风、急性或慢性白血病等。
推荐供应商
货号品牌产品名称规格包装、参考价格
A795452MACKLIN别嘌醇10mM in DMSO428元/1ml;   咨询
储存:-20°C
A800424MACKLIN别嘌醇98%38元/25g;   118元/100g;   498元/500g;   2398元/2.5kg;   咨询
储存:室温
状态:白色到灰白色粉末或块状
A0907TCIAllopurinol>98.0%(T)490元/25G;   1100元/250G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C5H4N4O = 136.11
外观与形状(20℃)固体
Reaxys-RN608611
PubChem物质ID87562416
SDBS (AIST Spectral DB)4122
Merck Index (14)279
MDL编号MFCD00599413

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Solubility in 1mol/L NaOHalmost transparency

物性(参考值)

熔点384 ℃
水溶性不溶
在水中的溶解度0.48 g/l   25 ℃
溶解性(不溶于)氯仿,乙醇,乙醚

安全信息

图形或危害标志
信号词危险
危险性说明H301 : 吞咽会中毒。
H317 : 可能造成皮肤过敏反应。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P272 : 受沾染的工作服不得带出工作场地。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P333 + P313 : 如发生皮肤刺激或皮疹:求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#UR0785000

运输信息

UN编号UN2811
类别6.1
包装类别 III
监管条件代码(*)
204337J&KAllopurinol98%149元/25G;   475元/100G;   1897元/500G;   咨询

基本信息

分子式C5H4N4O
分子量136.11
熔点>300
MDL编码MFCD00599413
Merck14,279
EINECS 编号206-250-9

安全信息

图形或危害标志
提示语Danger
危险说明H301
H317
防范说明P280
P301+P310
UN号码2811
危险分类6.1
包装等级III
WGK2
RTECSUR0785000
TSCA
A16974Alfa Aesar4-Hydroxy-1H-pyrazolo[3,4-d]pyrimidine98%846元/5g;   1705元/25g;   咨询

应用
Xanthine oxidase inhibitor; decreases uric acid production

基本信息

MDL
MFCD00599413

EINECS
206-250-9

分子式
C5H5N4O

分子量
136.11

熔点
>300°

灵敏度
Ambient temperatures.

形态
Powder

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H317
Toxic if swallowed.May cause an allergic skin reaction.

Precautionary Statements
P261-P280g-P301+P310a-P321-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves.Wear protective gloves.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
III

危险类别
25-43
Toxic if swallowed.May cause sensitization by skin contact.

安全等级
24-36/37-45
Avoid contact with skin.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

TSCA

C12183Alfa AesarAllopurinol98%537元/5g;   1282元/25g;   3502元/100g;   咨询

基本信息

Ref#
12183

MDL
599413

分子式
C5 H4 N4 O

分子量
136.11

安全信息

危险等级
6.1

包装组
III

A8003Sigma-AldrichAllopurinolxanthine oxidase inhibitor902.67元/5 G;   3448.53元/25 G;   咨询

产品说明

包装

5, 25 g in glass bottle

生化/生理作用

黄嘌呤氧化酶和初始嘧啶生物合成的抑制剂。治疗高尿酸血症和痛风的经典药物。

基本信息

经验(实验)分子式C5H4N4O
分子量136.11
EC 号206-250-9
MDL编号MFCD00599413
PubChem化学物质编号24278141
NACRESNA.77

产品性质

质量水平200
生物来源synthetic (organic)
测定≥99% (TLC)
形式powder
mp>300 ℃ (lit.)
溶解性1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
储存温度room temp
SMILES stringO=C1NC=Nc2[nH]ncc12
InChI1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI keyOFCNXPDARWKPPY-UHFFFAOYSA-N
Gene Informationhuman ... XDH(7498)

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H317
预防措施声明P280 - P301 + P310 + P330 - P302 + P352
危险分类Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
PHR1377SupelcoAllopurinolPharmaceutical Secondary Standard; Certified Reference Material1359.83元/1 G;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Allopurinol is a drug used in the treatment of chronic gout or hyperuricaemia. Its mode of action involves inhibition of xanthine oxidase, an important enzyme catalyzing the hydroxylation of hypoxanthine to xanthine and xanthine to uric acid.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Allopurinol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry.

生化/生理作用

黄嘌呤氧化酶和初始嘧啶生物合成的抑制剂。治疗高尿酸血症和痛风的经典药物。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA1633 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C5H4N4O
分子量136.11
EC 号206-250-9
MDL编号MFCD00599413
PubChem化学物质编号329823354
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp>300 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 870
traceable to PhEur A0350000
traceable to USP 1013002
储存温度2-30℃
SMILES stringO=C1NC=Nc2[nH]ncc12
InChI1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI keyOFCNXPDARWKPPY-UHFFFAOYSA-N
Gene Informationhuman ... XDH(7498)

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H317
预防措施声明P280 - P301 + P310 + P330 - P302 + P352
危险分类Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
A0350000AllopurinolEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

黄嘌呤氧化酶和初始嘧啶生物合成的抑制剂。治疗高尿酸血症和痛风的经典药物。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C5H4N4O
分子量136.11
MDL编号MFCD00599413
PubChem化学物质编号329770603
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp>300 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringO=C1NC=Nc2[nH]ncc12
InChI1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI keyOFCNXPDARWKPPY-UHFFFAOYSA-N
Gene Informationhuman ... XDH(7498)

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H317
预防措施声明P280 - P301 + P310 + P330 - P302 + P352
危险分类Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
1013002USPAllopurinolUnited States Pharmacopeia (USP) Reference Standard3231.47元/250 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

黄嘌呤氧化酶和初始嘧啶生物合成的抑制剂。治疗高尿酸血症和痛风的经典药物。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C5H4N4O
分子量136.11
MDL编号MFCD00599413
PubChem化学物质编号329748958
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp>300 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度15-25℃
SMILES stringO=C1NC=Nc2[nH]ncc12
InChI1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI keyOFCNXPDARWKPPY-UHFFFAOYSA-N
Gene Informationhuman ... XDH(7498)

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H317
预防措施声明P261 - P264 - P270 - P280 - P301 + P310 - P302 + P352
危险分类Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
BP870AllopurinolBritish Pharmacopoeia (BP) Reference Standard146.03元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

黄嘌呤氧化酶和初始嘧啶生物合成的抑制剂。治疗高尿酸血症和痛风的经典药物。

包装

Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C5H4N4O
分子量136.11
EC 号206-250-9
MDL编号MFCD00599413
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp>300 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringO=C1NC=Nc2[nH]ncc12
InChI1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI keyOFCNXPDARWKPPY-UHFFFAOYSA-N
Gene Informationhuman ... XDH(7498)

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H317
预防措施声明P280 - P301 + P310 + P330 - P302 + P352
危险分类Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
069190Fluorochem1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one97%220元/1g;   242元/25g;   572元/100g;   1804元/500g;   咨询

基本信息

CAS Number315-30-0
MDL NumberMFCD00599413
Melting Point>300℃

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P363: Wash contaminated clothing before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
Baidu
map