| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| A796703 | MACKLIN | 4-(2-氨乙基)苯磺酰氟盐酸盐溶液 | 10mg/mL in H2O | 220元/0.5ml; | 咨询 |
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| A796768 | MACKLIN | 4-(2-氨乙基)苯磺酰氟盐酸盐 | 10mM in DMSO | 198元/1ml; | 咨询 |
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| A796702 | MACKLIN | 4-(2-氨乙基)苯磺酰氟盐酸盐 | 50mg/mL in H2O | 512元/0.5ml; | 咨询 |
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| A800781 | MACKLIN | 4-(2-氨乙基)苯磺酰氟盐酸盐 | 98% | 77元/25mg; 244元/100mg; 699元/500mg; 999元/1g; 3999元/5g; 12984元/25g; | 咨询 |
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| A2215 | TCI | 4-(2-Aminoethyl)benzenesulfonyl Fluoride Hydrochloride [for Biochemical Research] | >99.0%(HPLC) | 620元/100MG; 3990元/1G; | 咨询 |
基本信息 | 纯度/分析方法 | >99.0%(HPLC) | | 分子式/分子量 | C8H10FNO2S・HCl = 239.69 | | 外观与形状(20℃) | 固体 | | 储存温度 | <0℃ | | 应避免的情况 | 加热 | | Reaxys-RN | 7604627 | | PubChem物质ID | 87561163 | | MDL编号 | MFCD00132962 |
技术规格 | Appearance | White to Almost white powder to crystal | | Purity(HPLC) | min. 99.0 area% | | Purity(with Total Nitrogen) | min. 97.0 % | | Enzyme inhibition test | to pass test |
物性(参考值) 安全信息 | 图形或危害标志 |  | | 信号词 | 危险 | | 危险性说明 | H314 : 造成严重皮肤灼伤和眼损伤。
H290 : 可能腐蚀金属。
| | 防范说明 | P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘或烟雾。
P234 : 只能在原容器中存放。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P390 : 吸收溢出物，防止材料损坏。
P303 + P361 + P353 : 如皮肤(或头发)沾染：立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P301 + P330 + P331 : 如误吞咽：漱口。不要诱导呕吐。
P363 : 沾染的衣服清洗后方可重新使用。
P304 + P340 + P310 : 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。立即呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。
P406 : 贮存于抗腐蚀/带抗腐蚀衬里的容器中。
P405 : 存放处须加锁。
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运输信息 | UN编号 | UN3261 | | 类别 | 8 | | 包装类别 | II | | 监管条件代码(*) | |
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| 554252 | J&K | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride | 99% | 447元/100MG; 1340元/500MG; 2277元/1G; | 咨询 |
基本信息 | 分子式 | C8H10FNO2S·HCl | | 分子量 | 239.69 | | 熔点 | 183 | | MDL编码 | MFCD00132962 | | Beilstein | 7604627 | | 存储条件 | Freezer -20℃ |
安全信息 | 图形或危害标志 | | | 提示语 | Danger | | 危险说明 | H314 | | 防范说明 | P280
P305+P351+P338
P310 | | UN号码 | 3261 | | 危险分类 | 8 | | 包装等级 | II | | WGK | 3 |
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| H26473 | Alfa Aesar | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride | 97% | 996元/250mg; 2947元/1g; | 咨询 |
应用
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation. 备注
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture. 基本信息 MDL
MFCD00132962 分子式
C8H10FNO2S?HCl 分子量
239.69 熔点
ca 184° dec. 灵敏度
Store at -20°C. Moisture Sensitive. 形态
Powder 溶解性
Soluble in water 50 mg/mL or 100% ethanol. Beilstein
7604627 GHS危害和防范说明 GHS符号
Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage. Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations. 安全信息 危险等级
8 包装组
III 危险类别
34
Causes burns. 安全等级
20-26-36/37/39-45
When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). 欧盟危险品标志
 TSCA
否 |
| C32811 | Alfa Aesar | AEBSF hydrochloride | 98% | 923元/50mg; 9270元/1g; | 咨询 |
基本信息 Ref#
32811 MDL
132962 分子式
C8 H10 F N O2 S . Cl H 分子量
239.7 安全信息 危险等级
8 包装组
II |
| BP26441 | Alfa Aesar | 4(2-AMINOETHYLBENZENESULFLU 1G | | 10291元/1g; | 咨询 |
基本信息 Ref#
F53164 安全信息 危险等级
8 包装组
II |
| BP264450 | Alfa Aesar | A (AMINOETHYL) BENZENESULF50MG | | 509元/50mg; | 咨询 |
基本信息 Ref#
F53160 安全信息 危险等级
8 包装组
II |
| BP635-500 | Alfa Aesar | AEBSF 500MG | | 3799元/500mg; | 咨询 |
基本信息 Ref#
F53532 安全信息 危险等级
8 包装组
II |
| BP2644500 | Alfa Aesar | 4(2AMINOETHYL)BENZENESULF500MG | | 2180元/500mg; | 咨询 |
基本信息 Ref#
F53152 安全信息 危险等级
8 包装组
II |
| BP2644100 | Alfa Aesar | 4(AMINOETHYLBENZENESULF 100MG | | 720元/100mg; | 咨询 |
基本信息 Ref#
F53186 安全信息 危险等级
8 包装组
II |
| BP635-100 | Alfa Aesar | AEBSF 100MG | | 1386元/100mg; | 咨询 |
基本信息 Ref#
F53464 安全信息 危险等级
8 包装组
II |
| 1.24839 | Millipore | Pefabloc® SC (4-(2-Aminoethyl)-benzolsulfonylfluorid-hydrochloride) | (AEBSF) for biochemistry | 775.7元/100 MG; 2310.93元/500 MG; | 咨询 |
产品说明 分析说明 Assay (HPLC): ≥ 98 %
Identity (IR-spectrum): passes test 法律信息 Pefabloc is a registered trademark of Pentapharm 基本信息 | 经验(实验)分子式 | C8H11ClFNO2S | | 分子量 | 239.69 | | MDL编号 | MFCD00132962 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98% (HPLC) | | mp | 175-177 ℃ | | 溶解性 | 10 g/L | | 堆积密度 | 200 kg/m3 | | 储存温度 | 2-8℃ | | InChI | 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H | | InChI key | WRDABNWSWOHGMS-UHFFFAOYSA-N |
安全信息 | 象形图 |  | | 警示用语： | Warning | | 危险声明 | H315 - H319 | | 预防措施声明 | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| SBR00015 | Sigma-Aldrich | AEBSF Ready Made Solution | | 825.15元/1 ML; | 咨询 |
产品说明 应用 该溶液以 100mM 水溶液形式提供。储备溶液可以 1：100 稀释至 1mM 工作浓度。建议使用浓度为 0.1-1.0 mM。 生化/生理作用 AEBSF 是一种特异性不可逆的丝氨酸蛋白酶抑制剂。它抑制凝乳蛋白酶、激肽酶、纤溶酶、凝血酶、胰蛋白酶和相关溶栓酶等蛋白酶。AEBSF 是现有丝氨酸蛋白酶抑制剂的极佳替代品，因为它具有优异的抑制活性和更低的毒理学风险。 其他说明 在较高的温度和 pH 值大于 7 时，AEBSF 的稳定性迅速下降。 基本信息 | 经验(实验)分子式 | C8H10FNO2S · HCl | | 分子量 | 239.69 | | MDL编号 | MFCD00132962 | | NACRES | NA.85 |
产品性质 | 测定 | ≥97% | | 质量水平 | 200 | | 形式 | liquid | | 储存条件 | protect from light | | 运输 | dry ice | | 储存温度 | −20℃ | | InChI | 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H | | InChI key | WRDABNWSWOHGMS-UHFFFAOYSA-N |
安全信息 | 储存分类代码 | 12 - Non Combustible Liquids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 76307 | Supelco | Pefabloc® SC | analytical standard | 1952.43元/100 MG; 7393.78元/500 MG; 12871.4元/1 G; | 咨询 |
产品说明 一般描述 Pefabloc® SC是一种胰蛋白酶抑制剂，可用于合成其精氨酸样类似物4-(2-胍基乙基)苯磺酰氟。
Pefabloc® SC是氨酸蛋白酶不可逆丝抑制剂，具有无毒强效、相对易使用的特点。据报道，在人和大鼠体内，均能有效抑制血小板活化因子(PAF)-降解乙酰水解酶(乙酰水解酶)。 应用 有关合适的仪器技术的更多信息，请参阅产品′的分析证书。想要获得更多支持，请联系技术服务部。
Pefabloc® SC可作为分析标准品，在有爪蟾蜍卵母细胞异源表达后，确定大鼠 NTPDase1和 NTPDase2 的天然寡聚物状态和底物特异性。也可用作酯酶抑制剂，添加至全血中改善环索奈德稳定性，用色谱-大气压化学电离-串联质谱(LC-APCI-MS / MS)法，测定人血浆中的环索奈德(CIC)及其活性代谢产物去异丁酰基环索奈德(des-CIC)。
建议使用浓度为 0.1 至 1mM。 生化/生理作用 不可逆的丝氨酸蛋白酶抑制剂。抑制常数与 PMSF 和 DFP 的抑制常数相似。AEBSF 可以抑制胰蛋白酶、糜蛋白酶、纤溶酶、激肽释放酶和凝血酶。作为 PMSF 和 DFP 的替代物，AEBSF 的毒性更低、水溶性和水溶液稳定性更好。AEBSF 已用于细胞培养，使用浓度可达 0.25mM。 其他说明 有效且不可逆的丝氨酸蛋白酶抑制剂；与PMSF不同，它是水溶性且无毒的；不受白蛋白影响 法律信息 Pefabloc is a registered trademark of Pentapharm 基本信息 | 经验(实验)分子式 | C8H10FNO2S · HCl | | 分子量 | 239.69 | | Beilstein | 7604627 | | MDL编号 | MFCD00132962 | | PubChem化学物质编号 | 329767025 | | NACRES | NA.24 |
产品性质 | 质量水平 | 200 | | 等级 | analytical standard | | 测定 | ≥95.0% (HPLC) | | 形式 | powder or crystals | | 保质期 | 5 yr | | technique(s) | HPLC: suitable
gas chromatography (GC): suitable | | application(s) | forensics and toxicology
pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | FS(C1=CC=C(CCN)C=C1)(=O)=O.[H]Cl | | InChI | 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H | | InChI key | WRDABNWSWOHGMS-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 | | 预防措施声明 | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 | | 储存分类代码 | 8A - Combustible, corrosive hazardous materials | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
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| 101500 | Sigma-Aldrich | AEBSF, Hydrochloride-CAS 30827-99-7-Calbiochem | AEBSF, CAS 30827-99-7, is a specific irreversible inhibitor of chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. A nontoxic alternative to PMSF and DFP. | 1090.74元/50 MG; 1560.15元/100 MG; 6127.99元/500 MG; 10842.4元/1 G; | 咨询 |
产品说明 一般描述 AEBSF, CAS 30827-99-7, is a specific irreversible inhibitor of chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. A nontoxic alternative to PMSF and DFP.
Specific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K.
Specific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications. Also available as a 50 mM solution in H2O (Cat. No. 508436). 包装 500 mg in Plastic ampoule
1 g in Glass bottle
50, 100 mg in Glass bottle
Packaged under inert gas 生化/生理作用 Primary Target
chymotrypsin
Product does not compete with ATP. 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 2 months at 4°C. Slight hydrolysis occurs at alkaline pH (8-9). 其他说明 Citron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol.109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol.23, 2247.
Markwardt, F., et al. 1973. Thromb. Res.2, 343.
Baker, B.R., and Cory, M. 1971. J. Med. Chem.14, 119. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息 | 经验(实验)分子式 | C8H10FNO2S · xHCl | | 分子量 | 203.23 (free base basis) | | MDL编号 | MFCD00132962 |
产品性质 | 质量水平 | 100 | | 测定 | >97% (HPLC) | | 形式 | solid | | manufacturer/tradename | Calbiochem® | | 储存条件 | OK to freeze
desiccated | | 颜色 | white to off-white | | 溶解性 | water: 25 mg/mL | | 运输 | ambient | | 储存温度 | −20℃ | | InChI | 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H | | InChI key | WRDABNWSWOHGMS-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 | | 预防措施声明 | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| A8456 | Sigma-Aldrich | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride | ≥97.0% (HPLC) | 778.85元/25 MG; 2361.17元/100 MG; 8352.1元/500 MG; | 咨询 |
产品说明 包装 25, 100, 500 mg in poly bottle 应用 建议使用浓度为 0.1 至 1mM。 生化/生理作用 不可逆的丝氨酸蛋白酶抑制剂。抑制常数与 PMSF 和 DFP 的抑制常数相似。AEBSF 可以抑制胰蛋白酶、糜蛋白酶、纤溶酶、激肽释放酶和凝血酶。作为 PMSF 和 DFP 的替代物，AEBSF 的毒性更低、水溶性和水溶液稳定性更好。AEBSF 已用于细胞培养，使用浓度可达 0.25mM。 基本信息 | 经验(实验)分子式 | C8H10FNO2S · HCl | | 分子量 | 239.69 | | Beilstein | 7604627 | | MDL编号 | MFCD00132962 | | PubChem化学物质编号 | 24278240 | | NACRES | NA.77 |
产品性质 | 质量水平 | 300 | | 生物来源 | synthetic (organic) | | 测定 | ≥97.0% (HPLC) | | 形式 | powder | | mp | 183-191 ℃ | | 溶解性 | H2O: 50 mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.) | | 储存温度 | −20℃ | | SMILES string | FS(C1=CC=C(CCN)C=C1)(=O)=O.[H]Cl | | InChI | 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H | | InChI key | WRDABNWSWOHGMS-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 | | 预防措施声明 | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 987372 | Amethyst | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride | 99%, 试剂级 | 92元/25MG; 261元/100MG; 912元/500MG; 1448元/1G; | 咨询 |
基本信息 | 分子式 | C8H10FNO2S·HCl | | 分子量 | 239.69 | | 熔点 | 183 | | MDL编码 | MFCD00132962 | | Beilstein | 7604627 | | 存储条件 | Freezer -20℃ |
安全信息 | 图形或危害标志 | | | 提示语 | Danger | | 危险说明 | H314 | | 防范说明 | P280
P305+P351+P338
P310 | | UN号码 | 3261 | | 危险分类 | 8 | | 包装等级 | II | | WGK | 3 |
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| M01245 | Fluorochem | AEBSF, Hydrochloride | 98% | 1540元/250mg; 2640元/1g; 9350元/5g; 17820元/10g; | 咨询 |
基本信息 | CAS Number | 30827-99-7 | | MDL Number | MFCD00132962 |
安全信息 | 图形或危害标志 | | | 危险性说明 | H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H314: Causes severe skin burns and eye damage.
H332: Harmful if inhaled.
| | 防范说明 | P260: Do not breathe
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to local regulations..
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