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CAS: 3063-71-6
分子式: C20H31N4O16P
分子量: 614.45
英文名称: 
cytidine monophosphate n-acetylneuraminic acid
推荐供应商
货号品牌产品名称规格包装、参考价格
C888637MACKLINCytidine-5'-monophospho-N-acetylneuraminic acid95%400元/1mg;   547元/5mg;   1048元/25mg;   3197元/100mg;   咨询
储存:-20°C,干燥,密封
状态:白色固体
C798929MACKLINCytidine-5'-monophospho-N-acetylneuraminic acid≥85%350元/1mg;   496元/5mg;   咨询
储存:-20°C
状态:白色粉末
C8271Sigma-AldrichCytidine-5′-monophospho-N-acetylneuraminic acid sodium salt≥85% (HPLC)1115.17元/1 MG;   4308.8元/5 MG;   15537.5元/25 MG;   咨询

产品说明

一般描述

Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is a sugar-nucleotide produced by CMP-Neu5Ac synthetase from CTP and Neu5Ac.

应用

Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt has been used:

  • as a standard in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for nucleotide sugar analysis in Joubert syndrome type 10 (JBTS10) patient cells and control skin fibroblasts,
  • As a substrate for the enzymatic sialylation of G2 glycoforms, resialylation assay,
  • in in-vitro sialyltransferase assay

包装

25 mg in poly bottle
1, 5 mg in glass bottle

生化/生理作用

Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is used as a substrate for Golgi sialyltransferases to form sialic acid and its conjugates.
胞苷-5′-单磷酸酯-N-乙酰基神经氨酸(CMP-唾液酸)是唾液酸转移酶的底物。主要用于多糖的酶促唾液酸化。

制备说明

通过Schauer, R.等人Hoppe Seyler′s Z. Physiol. Chem., 353, 883 (1972)的方法酶促制备。
CMP-NAN是非常酸不稳定的。

基本信息

线性分子式C20H31N4O16P
分子量636.43
Beilstein4224251
MDL编号MFCD00151579
PubChem化学物质编号24893038
NACRESNA.51

产品性质

质量水平200
测定≥85% (HPLC)
储存温度−20℃
SMILES string[Na+].CC(=O)N[C@@H]1[C@@H](O)C[C@@](O[C@@H]1[C@H](O)[C@H](O)CO)(OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(N)=NC3=O)C(O)=O
InChI1S/C20H31N4O16P.Na/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34;/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34);/q;+1/p-1/t8-,9+,10+,12+,13+,14+,15+,16?,17+,20+;/m0./s1
InChI keyVFRHSOGUONIUOR-CTFMUGKASA-M

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
5.05223Sigma-AldrichCMP-Sialic Acid, Disodium Salt InSolution-CAS 3063-71-6-Calbiochem3666.26元/10 mg;   咨询

产品说明

一般描述

CMP-sialic acid is the activated form of sialic acid that is required for the biosynthesis of sialic acid-containing complex carbohydrates. It is a widespread carbohydrate with numerous biological functions, including blood protein half-life regulation, variety of toxin neutralization, cellular adhesion and glycoprotein lytic protection.

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

外形

A 25 mM (10 mg/608 µL) sterile-filtered solution of CMP-Sialic Acid, Disodium Salt (Cat. No. 233264) in H₂O.

重悬

Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 1 year at -70°C.

其他说明

Schauer, R., et al. 1972. Hoppe Seylerʹs Z. Physiol. Chem.6, 353.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C20H29N4O16P · 2Na
分子量658.41
MDL编号MFCD00151579

产品性质

质量水平100
测定≥95% (HPLC)
形式liquid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
avoid repeated freeze/thaw cycles
protect from light
储存温度−70℃
InChI1S/C20H31N4O16P/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34)
InChI keyTXCIAUNLDRJGJZ-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
233264MilliporeCMP-Sialic Acid, Disodium Salt-CAS 3063-71-6-CalbiochemCMP-sialic acid is the activated form of sialic acid that is required for the biosynthesis of sialic acid-containing complex carbohydrates.3239.09元/5 MG;   10191.3元/25 MG;   咨询

产品说明

一般描述

CMP-sialic acid is the activated form of sialic acid that is required for the biosynthesis of sialic acid-containing complex carbohydrates. It is a widespread carbohydrate with numerous biological functions, including blood protein half-life regulation, variety of toxin neutralization, cellular adhesion and glycoprotein lytic protection. Also available as a 25 mM solution in H2O (Cat. No. 505223).

包装

5, 25 mg in Plastic ampoule

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Unstable under acidic conditions.

其他说明

Schauer, R., et al. 1972. Hoppe Seyler′s Z. Physiol. Chem.6, 353.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C20H29N4O16P · 2Na
分子量658.41
MDL编号MFCD00151579

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white
溶解性water: 20 mg/mL
运输wet ice
储存温度−20℃
InChI1S/C20H31N4O16P/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34)
InChI keyTXCIAUNLDRJGJZ-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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