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ä½ç½®ï¼šé¦–页 > 资料中心 > 化工字典 > 30516-87-1
关键è¯:       仅模糊查询
CAS: 30516-87-1
分å­å¼: C10H13N5O4
分å­é‡: 267.24
熔点: 113-115 °C(lit.)
中文å称: 
é½å¤šå¤«å®š
3'-å æ°®-3'-脱氧胸苷
英文å称: 
3'-azido-3'-deoxythymidine
azidothymidine
azt
bw a509u
bw-a 509u
retrovir
3'-azido-3'-deoxy-thymidin
zidovudine
azidodeoxythymidine
性质æè¿°: ç†”点106-112℃。
用途: æŠ—艾滋病和抗病毒原料è¯ã€‚
推è供应商
è´§å·å“牌产å“å称规格包装ã€å‚考价格
A795496MACKLIN3'-å æ°®-3'-脱氧胸苷10mM in DMSO185å…ƒ/1ml;   咨询
储存：-20°C
状æ€ï¼šæ¶²ä½“
A801675MACKLIN3'-å æ°®-3'-脱氧胸苷99%59å…ƒ/1g;   170å…ƒ/5g;   545å…ƒ/25g;   1906å…ƒ/100g;   咨询
储存：-20°C
状æ€ï¼šNA
折射率：47 ° (C=1, H2O)
A2052TCI3'-Azido-3'-deoxythymidine>98.0%(T)610å…ƒ/1G;   1250å…ƒ/5G;   咨询

基本信æ¯

纯度/分æžæ–¹æ³•>98.0%(T)
分å­å¼/分å­é‡C10H13N5O4 = 267.25
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应é¿å…的情况湿气 (å¸æ¹¿)
Reaxys-RN3595791
PubChem物质ID87559740
SDBS (AIST Spectral DB)51948
Merck Index (14)10123
MDLç¼–å·MFCD00006536

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Neutralization titration)min. 98.0 %
Melting point122.0 to 126.0 ℃
Specific rotation [a]20/D+43.0 to +51.0 deg(C=1, H2O)

物性(å‚考值)

熔点124 ℃
比旋光度 [α]D47° (C=1,H2O)
水溶性微溶
在水中的溶解度20 g/l   25 ℃
溶解性(å¯æº¶äºŽ)乙醇

安全信æ¯

图形或å±å®³æ ‡å¿—
ä¿¡å·è¯è­¦å‘Š
å±é™©æ€§è¯´æ˜ŽH303 : åžå’½å¯èƒ½æœ‰å®³ã€‚
H351 : 怀疑致癌。
防范说明P501 : 将内装物/容器é€åˆ°æ‰¹å‡†çš„废物处ç†åŽ‚处ç†ã€‚
P202 : 在阅读并明了所有安全措施å‰åˆ‡å‹¿æ¬åŠ¨ã€‚
P201 : 使用å‰å–得专用说明。
P280 : 戴防护手套/穿防护æœ/戴防护眼罩/戴防护é¢å…·ã€‚
P312 : 如感觉ä¸é€‚，呼å«æ€¥æ•‘中心/医生。
P405 : 存放处须加é”。

相关法规

RTECS#XP2072000
431574J&K3'-Azido-3'-deoxythymidine(Zidovudine)98%170å…ƒ/250MG;   561å…ƒ/1G;   1159å…ƒ/5G;   咨询

基本信æ¯

分å­å¼C10H13N5O4
分å­é‡267.24
熔点113-115
MDLç¼–ç MFCD00006536
Beilstein3595791
Merck14,10123
存储æ¡ä»¶Freezer -20℃

安全信æ¯

图形或å±å®³æ ‡å¿—
æ示语Warning
å±é™©è¯´æ˜ŽH351
防范说明P281
WGK3
RTECSXP2072000
PHR1292SupelcoZidovudinePharmaceutical Secondary Standard; Certified Reference Material1495.61å…ƒ/1 G;   咨询

产å“说明

一般æè¿°

用于质é‡æŽ§åˆ¶çš„已认è¯çš„è¯ç‰©äºŒçº§æ ‡å‡†ï¼Œä¸ºåˆ¶è¯å®žéªŒå®¤å’Œåˆ¶é€ å•†æ供了è¯å…¸åŸºæœ¬æ ‡å‡†çš„一ç§æ–¹ä¾¿ä¸”æˆæœ¬æ•ˆç›Šå¥½çš„替代å“。
é½å¤šå¤«å®š(AZT)是一ç§èƒ¸è…ºå˜§å•¶æ ¸è‹·ç±»ä¼¼ç‰©æŠ—HIVè¯ç‰©ï¼Œå·²çŸ¥å¯é™ä½ŽHIV感染患者的死亡率。其作用方å¼æ¶‰åŠåˆ°æŠ‘制病毒逆转录酶的活性并阻断HIVçš„å¤åˆ¶ã€‚
用于质é‡æŽ§åˆ¶çš„ç»è®¤è¯çš„è¯ç‰©äºŒçº§æ ‡å‡†ä¸ºåˆ¶è¯å®žéªŒå®¤å’Œåˆ¶é€ å•†æ供了一ç§æ–¹ä¾¿ä¸”具有æˆæœ¬æ•ˆç›Šçš„è¯å…¸ä¸»è¦æ ‡å‡†æ›¿ä»£å“。

应用

é½å¤šå¤«å®šå¯ç”¨ä½œè¯ç‰©å‚考标准å“，通过色谱和分光光度技术对è¯ç‰©åˆ¶å‰‚ã€ç‰‡å‰‚å’Œè¯ç‰©å‰‚型中的分æžç‰©è¿›è¡Œæµ‹å®šã€‚
这些二级标准å“是åˆæ ¼çš„认è¯æ ‡å‡†ç‰©è´¨(CRM)。它们适用于多ç§åˆ†æžåº”用，包括但ä¸é™äºŽè¯ç‰©é‡Šæ”¾æµ‹è¯•ã€è¯ç‰©çš„定性和定é‡åˆ†æžæ–¹æ³•å¼€å‘ã€é£Ÿå“和饮料质é‡æŽ§åˆ¶æ£€æµ‹ä»¥åŠå…¶ä»–校准需求。

生化/生ç†ä½œç”¨

对 HIV-1 病毒有效的逆转录酶抑制剂。

分æžè¯´æ˜Ž

这些二级标准å“å¯è¿½æº¯è‡³USPã€EP(PhEur)å’ŒBP一级标准å“。

其他说明

该认è¯å‚考物质(CRM)æ ¹æ® ISO 17034 å’Œ ISO/IEC 17025 进行生产和认è¯ã€‚所有关于 CRM çš„ä¿¡æ¯éƒ½å¯ä»¥åœ¨åˆ†æžè¯ä¹¦ä¸Šæ‰¾åˆ°ã€‚

附注

欲查看该æ料的分æžè¯ä¹¦ç¤ºä¾‹ï¼Œè¯·åœ¨ä¸‹é¢çš„æ ä½ä¸­è¾“å…¥ LRAA0303。这åªæ˜¯ä¸€ä¸ªç¤ºä¾‹è¯ä¹¦ï¼Œå¯èƒ½ä¸æ˜¯æ‚¨æ”¶åˆ°çš„批次。

基本信æ¯

ç»éªŒ(实验)分å­å¼C10H13N5O4
分å­é‡267.24
Beilstein3595791
MDLç¼–å·MFCD00006536
PubChem化学物质编å·329823283

产å“性质

è´¨é‡æ°´å¹³300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp113-115 â„ƒ (lit.)
application(s)pharmaceutical (small molecule)
æ ¼å¼neat
è¯å…¸å¯è¿½æº¯æ€§traceable to BP 803
traceable to PhEur Z1900000
traceable to USP 1724500
储存温度2-8℃
SMILES stringCC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI keyHBOMLICNUCNMMY-XLPZGREQSA-N

安全信æ¯

储存分类代ç 11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Z1900000ZidovudineEuropean Pharmacopoeia (EP) Reference Standard1572.27å…ƒ/ ;   咨询

产å“说明

一般æè¿°

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生ç†ä½œç”¨

对 HIV-1 病毒有效的逆转录酶抑制剂。

包装

Unit quantity: 60 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注æ„

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信æ¯

ç»éªŒ(实验)分å­å¼C10H13N5O4
分å­é‡267.24
Beilstein3595791
MDLç¼–å·MFCD00006536
PubChem化学物质编å·329831604
NACRESNA.24

产å“性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp113-115 â„ƒ (lit.)
application(s)pharmaceutical (small molecule)
æ ¼å¼neat
储存温度2-8℃
SMILES stringCC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI keyHBOMLICNUCNMMY-XLPZGREQSA-N

安全信æ¯

储存分类代ç 11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
A2169Sigma-Aldrich3′-Azido-3′-deoxythymidine≥98% (HPLC)1068.12å…ƒ/25 MG;   3314.92å…ƒ/100 MG;   4892.2å…ƒ/250 MG;   14815.4å…ƒ/1 G;   咨询

产å“说明

应用

3′-å æ°®-3′-脱氧胸苷已作为逆转录酶抑制剂抑制病毒基因组整åˆå’Œä½œä¸ºæŠ—èŒå‰‚评估其抗沙门æ°èŒæ´»æ€§ã€‚

包装

1 g in glass bottle
25 mg in glass insert
100, 250 mg in glass bottle

生化/生ç†ä½œç”¨

å æ°®èƒ¸è‹· (AZT) 是一ç§èƒ¸è‹·ç±»ä¼¼ç‰©ï¼Œæ˜¯ HIV-1 病毒的逆转录酶抑制剂。å æ°®èƒ¸è‹·å·²è¢«è¯æ˜Žä¼šé™ä½Ž CRISPR 介导的åŒæºå®šå‘ä¿®å¤ (HDR) 的效率。
对 HIV-1 病毒有效的逆转录酶抑制剂。

特点和优势

è¿™ç§åŒ–åˆç‰©æ˜¯ADME毒性研究的特色产å“。点击此处å‘现更多特色ADME毒性产å“。在sigma.com/discover-bsmå¯äº†è§£æ›´å¤šå…³äºŽç”Ÿç‰©æ´»æ€§å°åˆ†å­çš„其他研究领域。

基本信æ¯

ç»éªŒ(实验)分å­å¼C10H13N5O4
分å­é‡267.24
Beilstein3595791
MDLç¼–å·MFCD00006536
PubChem化学物质编å·24278143
NACRESNA.77

产å“性质

è´¨é‡æ°´å¹³200
测定≥98% (HPLC)
å½¢å¼powder
mp113-115 â„ƒ (lit.)
溶解性H2O: 50 mg/mL
web metadata keyword.defaultAzidothymidine; AZT; Zidovudine, ZDV; 3′-Azido-3′-Deoxythymidine; 30516-87-1; retroviral; reverse transcriptase inhibitor; genotoxin; TK; AZTTP; AZTMP; mitochondrial dna polymerase; hypermethylation.
储存温度−20℃
SMILES stringCC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI keyHBOMLICNUCNMMY-XLPZGREQSA-N
Gene Informationhuman ... HIVE1(3095)
mouse ... Slc29a1(63959)

安全信æ¯

储存分类代ç 11 - Combustible Solids
WGKWGK 3
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Y0002266Zidovudine for system suitability ACRS, European Pharmacopoeia (EP) Reference Standard1341.2å…ƒ/ ;   咨询

产å“说明

一般æè¿°

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pha

生化/生ç†ä½œç”¨

对 HIV-1 病毒有效的逆转录酶抑制剂。

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信æ¯

ç»éªŒ(实验)分å­å¼C10H13N5O4
分å­é‡267.24
Beilstein3595791
MDLç¼–å·MFCD00006536

产å“性质

manufacturer/tradenameEDQM
mp113-115 â„ƒ (lit.)
储存温度2-8℃
SMILES stringCC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI keyHBOMLICNUCNMMY-XLPZGREQSA-N

安全信æ¯

储存分类代ç 11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1724500USPZidovudineUnited States Pharmacopeia (USP) Reference Standard3231.47å…ƒ/400 MG;   咨询

产å“说明

一般æè¿°

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生ç†ä½œç”¨

对 HIV-1 病毒有效的逆转录酶抑制剂。

分æžè¯´æ˜Ž

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信æ¯

ç»éªŒ(实验)分å­å¼C10H13N5O4
分å­é‡267.24
Beilstein3595791
MDLç¼–å·MFCD00006536
PubChem化学物质编å·329751524
NACRESNA.24

产å“性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp113-115 â„ƒ (lit.)
application(s)pharmaceutical (small molecule)
æ ¼å¼neat
储存温度2-8℃
SMILES stringCC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI keyHBOMLICNUCNMMY-XLPZGREQSA-N

安全信æ¯

储存分类代ç 11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP895Zidovudine impurity standardBritish Pharmacopoeia (BP) Reference Standard1989å…ƒ/25 MG;   咨询

产å“说明

一般æè¿°

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生ç†ä½œç”¨

对 HIV-1 病毒有效的逆转录酶抑制剂。

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信æ¯

ç»éªŒ(实验)分å­å¼C10H13N5O4
分å­é‡267.24
Beilstein3595791
MDLç¼–å·MFCD00006536

产å“性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp113-115 â„ƒ (lit.)
æ ¼å¼mixture
储存温度2-8℃
SMILES stringCC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI keyHBOMLICNUCNMMY-XLPZGREQSA-N

安全信æ¯

储存分类代ç 11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
998003Amethyst3'-Azido-3'-deoxythymidine98%, 试剂级45å…ƒ/250MG;   98å…ƒ/1G;   269å…ƒ/5G;   572å…ƒ/25G;   咨询

基本信æ¯

分å­å¼C10H13N5O4
分å­é‡267.24
熔点113-115
MDLç¼–ç MFCD00006536
Beilstein3595791
Merck14,10123
存储æ¡ä»¶Freezer -20℃

安全信æ¯

图形或å±å®³æ ‡å¿—
æ示语Warning
å±é™©è¯´æ˜ŽH351
防范说明P281
WGK3
RTECSXP2072000
358376Fluorochem1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione= 99% (assay)286å…ƒ/1g;   704å…ƒ/5g;   1958å…ƒ/25g;   6160å…ƒ/100g;   咨询

基本信æ¯

CAS Number30516-87-1
MDL NumberMFCD00006536
Melting Point124℃

安全信æ¯

图形或å±å®³æ ‡å¿—
å±é™©æ€§è¯´æ˜Ž H351: Suspected of causing cancer ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
CASå·é¦–数字顺åºæŽ’列： 1 2 3 4 5 6 7 8 9
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