Technical Notes:

1. New generation of chiral biaryl phosphine ligands with tunable dihedral angles. The ability to

modify the dihedral angle allows for the fine tuning of the catalyst system and optimization of en antioselectivity.

2.Ru-C3-TUNEPHOS complexes are used for asymmetric hydrogenation of ß-ketoesters ', enol acetates?, cyclic ß-amino acids3, a-phthalimide ketones, and a-keto esters.

3.Rh-catalyzed hydroformylation of cyclopropenes .

References:

1.J. Org. Chem., 2000, 65, 6223.

2.Org. Lett., 2002, 4, 4495.

3.J. Am. Chem. Soc., 2003, 125, 9570.

4.J. Am. Chem. Soc., 2004, 126, 1626.

5.Synlett 2006, 126, 1 169

6.J. Am. Chem. Soc., 2008, 130, 13804.