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CAS: 2566-34-9
分子式: C5H11NO2
分子量: 117.14
熔点: 300℃
英文名称: 
2-(methylamino)isobutyric acid
α-(Methylamino)isobutyric acid
2,N-Dimethylalanine
N,2-Dimethylalanine
推荐供应商
货号品牌产品名称规格包装、参考价格
M862527MACKLIN2-(甲氨基)异丁酸水合物≥98%(T)465元/250mg;   1485元/1g;   咨询
储存:室温,干燥
状态:白色-几乎白色晶体-粉末固体
M1388TCI2-(Methylamino)isobutyric Acid>98.0%(T)1350元/1G;   3490元/5G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C5H11NO2 = 117.15
外观与形状(20℃)固体
Reaxys-RN1746984
PubChem物质ID87573341
MDL编号MFCD00004191

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %
Solubility in Wateralmost transparency

安全信息

图形或危害标志
信号词警告
危险性说明H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护眼罩/戴防护面具。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
M2383Sigma-Aldrichα-(Methylamino)isobutyric acid≥97% (titration)642.73元/250 MG;   1251元/1 G;   咨询

产品说明

应用

α-(Methylamino)isobutyric acid (MeAIB) has been used:

  • as a system A transport system inhibitor to perform inhibition experiments
  • as a system A transport system inhibitor to study its effect on the generation of epileptiform field potentials (EFPs) in the acutely disinhibited cortical slices
  • as an N-acetyltransferase (SNAT) inhibitor in Hank′s balanced salt solution (HBSS) to study its influence on the uptake of 14C-cysteine/ radioactive-labeled cysteine

包装

250 mg in poly bottle
1 g in poly bottle

生化/生理作用

α-(Methylamino)isobutyric acid (MeAIB), a competitive inhibitor of the neutral amino acid transport A system, is an N-methylated substrate. It is capable of decreasing the amplitude of the miniature excitatory postsynaptic current (mEPSC) in hippocampus neurons developing on top of astrocytes. MeAIB can block the alanine-proline (AP) pathway.

基本信息

线性分子式CH3NHC(CH3)2COOH
分子量117.15
Beilstein1746984
EC 号219-898-2
MDL编号MFCD00004191
PubChem化学物质编号24896726
NACRESNA.26

产品性质

质量水平100
测定≥97% (titration)
形式powder
technique(s)ligand binding assay: suitable
颜色 white
mp>300 ℃ (lit.)
储存温度−20℃
SMILES stringCNC(C)(C)C(O)=O
InChI1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8)
InChI keyDLAMVQGYEVKIRE-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
300063Fluorochem2-(Methylamino)isobutyric acid hydrate>98.0%(T)2266元/1g;   5566元/5g;   咨询

基本信息

CAS Number2566-34-9
MDL NumberMFCD00004191

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
492960FluorochemN-Methyl-a-aminoisobutyric acid hydrochloride= 98% (TLC)2244元/1g;   6710元/5g;   11748元/10g;   23474元/25g;   咨询

基本信息

CAS Number2566-34-9
MDL NumberMFCD06795786
Melting Point188-197℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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