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CAS: 2192-20-3
分子式: C21H27ClN2O2·2HCL
分子量: 447.83
中文名称: 
安泰乐
羟嗪盐酸盐
英文名称: 
2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-ethano dihydro
hydroxyzine dihydrochloride
neurolax
orgatrax
tran-q dihydrochloride
tranquizine dihydrochloride
vistaril steraject
2-[2-[4-[(4-Chlorophenyl)Phenylmethyl]-1-Piperazinyl]ethoxy]ethanol
2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)-ethano dihydroc
2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol dihydrochl
alamon
atarax dihydrochloride
ataraxoid dihydrochloride
aterax dihydrochloride
dichlorhydrate de 1-p.chlorbenzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine
展开更多英文名
性质描述: 白色结晶性粉末。熔点193℃。易溶于水,溶于乙醇,不溶于乙醚。无臭,味苦。
生产方法: 由1-[2-(2-羟乙氧基)乙基]哌嗪(见21815)与对氯二苯氯甲烷缩合、成盐而得。
用途: 具有安定及松驰横纹肌的作用,也有抗组织织胺作用和胆碱作用,适用于轻度紧张、焦虑、不安。
推荐供应商
货号品牌产品名称规格包装、参考价格
H797532MACKLINHydroxyzine 2HCl10mM in DMSO186元/1ml;   咨询
储存:-20°C
H873785MACKLINHydroxyzine 2HCl99%72元/1g;   240元/5g;   咨询
储存:-20℃
状态:粉末
589276J&KHydroxyzine dihydrochloride98%979元/10G;   2154元/25G;   7095元/100G;   咨询

基本信息

分子式C21H27ClN2O2·2HCl
分子量447.83
MDL编码MFCD00058200
EINECS 编号218-586-3

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSKK2280000
C46844Alfa AesarHydroxyzine dihydrochloride1336元/1g;   2674元/5g;   咨询

基本信息

分子式
C21 H27 Cl N2 O2 . 2 HCl

分子量
447.83

PHR1607SupelcoHydroxyzine dihydrochloridePharmaceutical Secondary Standard; Certified Reference Material1518.26元/1 G;   咨询

产品说明

一般描述

Hydroxyzine dihydrochloride is an antihistaminic drug and a member of the diphenylmethanes family. It exerts its action by blocking the action of histamine, a substance in the body that causes allergic symptoms.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Hydroxyzine dihydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by spectrophotometry and high performance liquid chromatography.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA4723 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C21H27ClN2O2 · 2HCl
分子量447.83
EC 号218-586-3
MDL编号MFCD00058200
PubChem化学物质编号329823504

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 841
traceable to PhEur H1435000
traceable to USP 1333003
储存温度2-8℃
SMILES stringCl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI keyANOMHKZSQFYSBR-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H336 - H361d
预防措施声明P202 - P261 - P264 - P270 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
靶器官Central nervous system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
H8885Sigma-AldrichHydroxyzine dihydrochloride≥97%1353.36元/10 g;   咨询

产品说明

一般描述

Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist.

应用

Hydroxyzine dihydrochloride has been used in the study of comparative anxiolytic activity of various drugs in experimental models of rats.

生化/生理作用

Hydroxyzine dihydrochloride (HDH) is used to regulate anxiety. It is also used to treat bronchial asthma and to relax patients before surgery.

基本信息

经验(实验)分子式C21H27ClN2O2 · 2HCl
分子量447.83
EC 号218-586-3
MDL编号MFCD00058200
PubChem化学物质编号24895830
NACRESNA.77

产品性质

质量水平200
测定≥98%
形式powder
溶解性H2O: soluble
alcohol: soluble
chloroform: soluble
SMILES stringCl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI keyANOMHKZSQFYSBR-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H336 - H361d
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
靶器官Central nervous system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
H1435000Hydroxyzine hydrochlorideEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 600 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H27ClN2O2 · 2HCl
分子量447.83
MDL编号MFCD00058200
PubChem化学物质编号329815164
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI keyANOMHKZSQFYSBR-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H336 - H361d
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
靶器官Central nervous system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP841Hydroxyzine hydrochlorideBritish Pharmacopoeia (BP) Reference Standard1916.08元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H27ClN2O2 · 2HCl
分子量447.83
MDL编号MFCD00058200

产品性质

等级pharmaceutical primary standard
质量British Pharmacopoeia (BP) Reference Standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI keyANOMHKZSQFYSBR-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H336 - H361d
预防措施声明P201 - P202 - P261 - P280 - P304 + P340 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
靶器官Central nervous system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1333003USPHydroxyzine hydrochlorideUnited States Pharmacopeia (USP) Reference Standard3231.47元/500 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C21H27ClN2O2 · 2HCl
分子量447.83
MDL编号MFCD00058200
PubChem化学物质编号329750139
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI keyANOMHKZSQFYSBR-UHFFFAOYSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H336 - H361d
预防措施声明P201 - P202 - P261 - P280 - P304 + P340 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
靶器官Central nervous system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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