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CAS: 1976038-41-1
英文名称: 
tp-008
2-(1-(2-(5-chloro-2-fluorophenyl)-5-methylpyridin-4-yl)-2-oxo-1h-imidazo[4,5-c]pyridin-3(2h)-yl)acetamide
1-[2-(5-chloro-2-fluorophenyl)-5-methyl-4-pyridinyl]-1,2-dihydro-2-oxo-3h -imidazo[4,5-c ]pyridine-3-acetamide
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货号品牌产品名称规格包装、参考价格
SML2705Sigma-AldrichTP-008≥98% (HPLC)1376.29元/5 MG;   5320.12元/25 MG;   咨询

产品说明

生化/生理作用

SGC Frankfurt Pharma donated probe. TP-008 is a cell penetrant, potent and selective ALK4/5 ((activin-like kinase 4/5) dual inhibitor that potently inhibits SMAD2/3 phosphorylation in C2C12 cells. TP-008 exhibits significant cardiac toxicity in mice. It is compound 18 in BMCL 2016 paper.

基本信息

经验(实验)分子式C20H15ClFN5O2
分子量411.82

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9
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