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CAS: 196808-24-9
分子式: C30H29N3O4
分子量: 495.57
英文名称: 
gw1929
用途: GW1929是有效的 PPAR-γ 激动剂,对人 PPAR-γ 的 pKi 为8.84。对人和鼠的 pEC50 分别为8.56 和 8.27。
推荐供应商
货号品牌产品名称规格包装、参考价格
G880826MACKLINGW1929 99%870元/5mg;   1623元/10mg;   咨询
储存:2-8℃
状态:黄色固体
370695Sigma-AldrichGW1929-CAS 196808-24-9-CalbiochemA potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivatio4822.81元/1 MG;   咨询

产品说明

一般描述

A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).
A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine PPARγ and 6.2 nM for human PPARγ in cell-based transactivation assays).

包装

1 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Peroxisome proliferator-activated receptor γ (PPARγ) agonist
EC50 = 13 nM as peroxisome proliferator-activated receptor γ (PPARγ) agonist for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Han, S., et al. 2004. Clin. Cancer Res.10, 1911.
Willson, T.M., et al. 2000. J. Med. Chem.43, 527.
Brown, K.K., et al. 1999. Diabetes48, 1415.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C30H29N3O4
分子量495.57

产品性质

质量水平100
测定≥97% (NMR)
形式crystalline solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 yellow
溶解性DMSO: 100 mg/mL
运输ambient
储存温度−20℃
InChI1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18,27,32H,19-21H2,1H3,(H,35,36)/t27-/m0/s1
InChI keyQTQMRBZOBKYXCG-MHZLTWQESA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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