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CAS: 188062-50-2
分子式: C28H38N12O6S
分子量: 670.74
中文名称: 
硫酸阿巴卡韦 硫酸酯
英文名称: 
abacavir for peak identification
abacavir sulfate
推荐供应商
货号品牌产品名称规格包装、参考价格
A794725MACKLIN阿巴卡韦硫酸盐10mM in Water706元/1ml;   咨询
储存：-20°C
A833205MACKLIN阿巴卡韦硫酸盐99%52元/10mg;   70元/50mg;   159元/250mg;   395元/1g;   咨询
储存：-20°C
状态：白色到棕褐色固体
Y0001552Abacavir for peak identificationEuropean Pharmacopoeia (EP) Reference Standard1594.77元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C28H36N12O2 · H2SO4
分子量670.74
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P201 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0001551Abacavir for system suitabilityEuropean Pharmacopoeia (EP) Reference Standard1304.74元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C28H36N12O2 · H2SO4
分子量670.74
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P201 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR1256SupelcoAbacavir sulfatePharmaceutical Secondary Standard; Certified Reference Material2222.07元/500 MG;   咨询

产品说明

一般描述

Abacavir sulfate belongs to the class of human immunodeficiency virus (HIV) medicines called nucleoside reverse transcriptase inhibitors, with antiretroviral activity against HIV.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Abacavir sulfate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-peformance liquid chromatography technique and spectrophotometric technique.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3642 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C28H36N12O2 · H2SO4
分子量670.74
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to PhEur Y0001561
traceable to USP 1000408
储存温度2-30℃
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P201 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1000408USPAbacavir sulfateUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C28H36N12O2 · H2SO4
分子量670.74
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P201 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP1112Abacavir sulfateBritish Pharmacopoeia (BP) Reference Standard1916.08元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C28H36N12O2 · H2SO4
分子量670.74

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P201 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0001561Abacavir sulfateEuropean Pharmacopoeia (EP) Reference Standard1861.35元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C28H36N12O2 · H2SO4
分子量670.74
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P280 - P305 + P351 + P338
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
SML0089Sigma-AldrichAbacavir sulfate≥98% (HPLC)1118.38元/10 MG;   4510.54元/50 MG;   咨询

产品说明

一般描述

阿巴卡韦具有抗病毒活性。它与心肌梗塞和致命性超敏反应(HSR)相关。

应用

硫酸阿巴卡韦已用作化合物来验证小鼠中的 P19C5 胃泌素。它也已用于诱导染色体双链断裂(DSBs)并杀死成人 T 细胞白血病(ATL)细胞。
硫酸阿巴卡韦已用于细胞毒性实验，以测试其在 U937 细胞中的促肿瘤活性。

包装

10 mg in glass bottle
50 mg in poly bottle

生化/生理作用

硫酸阿巴卡韦是一种核苷类似物逆转录酶抑制剂(NRTI)；鸟苷类似物，用于治疗 HIV 和 AIDS。
掺入细胞中的阿巴卡韦被转化为含有鸟嘌呤类似物卡波韦(CBV)的三磷酸，它有助于产生更高的双链断裂(DSB)。

特点和优势

该化合物由GlaxoSmithKline开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。
这种化合物是ADME毒性研究的特色产品。点击此处发现更多特色ADME毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

基本信息

经验(实验)分子式C14H18N6O · 0.5 H2SO4
分子量335.37
MDL编号MFCD04112763
PubChem化学物质编号329825149
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
旋光性[α]/D -30 to -40°, c = 0.5 in methanol
颜色 white to tan
溶解性H2O: ≥17 mg/mL
创始人GlaxoSmithKline
储存温度2-8℃
SMILES stringOS(O)(=O)=O.Nc1nc(NC2CC2)c3ncn([C@@H]4C[C@H](CO)C=C4)c3n1.Nc5nc(NC6CC6)c7ncn([C@@H]8C[C@H](CO)C=C8)c7n5
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P201 - P202 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP1113Abacavir impurity standardBritish Pharmacopoeia (BP) Reference Standard1989元/10 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C28H36N12O2 · H2SO4
分子量670.74

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式mixture
储存温度2-8℃
InChI1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChI keyWMHSRBZIJNQHKT-FFKFEZPRSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H317 - H319 - H341 - H351 - H361
预防措施声明P201 - P202 - P261 - P280 - P308 + P313 - P333 + P313
危险分类Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
510486FluorochemAbacavir sulfate98%990元/5mg;   1320元/10mg;   2442元/50mg;   3410元/100mg;   咨询

基本信息

CAS Number188062-50-2
MDL NumberMFCD17215524
Melting Point222-225℃

安全信息

图形或危害标志
危险性说明 H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H341: Suspected of causing genetic defects ..
H351: Suspected of causing cancer ..
H361: Suspected of damaging fertility or the unborn child ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P261: Avoid breathing .
P264: Wash thoroughly after handling.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear .
P281: Use personal protective equipment as required.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P321: Specific treatment (see . on this label).
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to local regulations..
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