CAS 160296-13-9; sb 205384 - �뵺�羺�ٷ��ַ

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CAS:

160296-13-9

英文名称:

sb 205384

4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester

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货号

品牌

产品名称

规格

包装、参考价格

S7936

Sigma-Aldrich

SB 205384

solid

2440.31元/5 MG;

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产品说明

应用

SB 205384 was used to study GABA-gated currents in rat locus coeruleus neurons.⁶

生化/生理作用

SB 205384 is a selective and positive allosteric modulator of non-benzodiazepine site of the GABA_A receptor.³ It affects the extrasynaptic GABA_A receptors in rat cortical neurons⁴ and enhances the GABAergic transmission onto pro-opiomelanocortin neurons in mice.⁵
GABA_A receptor modulator selective for the α₃β₂γ₂ subunit combination.

法律信息

Manufactured and sold under license from GlaxoSmithKline Pharmaceuticals

基本信息

经验(实验)分子式	C₁₇H₁₈N₂O₃S
分子量	330.40
MDL编号	MFCD00918851
PubChem化学物质编号	24278711
NACRES	NA.77

产品性质

质量水平	100
形式	solid
颜色	off-white
溶解性	DMSO: 18 mg/mL H₂O: insoluble
SMILES string	CC#CCOC(=O)c1c(C)nc2sc3CC(O)CCc3c2c1N
InChI	1S/C17H18N2O3S/c1-3-4-7-22-17(21)13-9(2)19-16-14(15(13)18)11-6-5-10(20)8-12(11)23-16/h10,20H,5-8H2,1-2H3,(H2,18,19)
InChI key	JDTZAGLGBRRCJT-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

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