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CAS: 154-17-6
分子式: C6H12O5
分子量: 164.16
熔点: 146-147℃
中文名称: 
2-去氧-D-葡糖
2-脱氧-D-葡糖
D-2-脱氧葡萄
二脱氧葡萄糖
2-脱氧-D-葡萄糖
2-去氧-D-葡萄糖
2-脱氧葡萄糖
D-2-脱氧葡萄糖
英文名称: 
2-deoxy-d-arabino-hexos
2-deoxy-d-arabino-hexose
2-deoxy-d-glucose
2-deoxy-d-mannose
2-deoxyglucose
2-desoxy-d-glucose
2-dg
ba 2758
d-2-deoxyglucose
2-deoxy-d-glucos
deoxyglucose
2-deoxy-glucos
nsc 15193
2-Deoxy-D-arabinohexose
2-deoxy-glucose
D-Arabino-2-deoxyhexose
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格
D798411MACKLIN2-脱氧-D-葡萄糖10mM in DMSO778元/1ml;   咨询
储存:-20°C
D807272MACKLIN2-脱氧-D-葡萄糖98%59元/1g;   219元/5g;   795元/25g;   2425元/100g;   咨询
储存:2~8℃
状态:白色到灰白色粉末
折射率:46.5 ° (C=1, H2O)
156916J&K2-Deoxy-D-glucose98%230元/1G;   781元/5g;   咨询

基本信息

分子式C6H12O5
分子量164.16
熔点146-147
比旋光度([α]20D)+45.0° to +47.5° (C=2, H2O)
MDL编码MFCD00151328
Beilstein1723331
Merck14,2904
EINECS 编号205-823-0

安全信息

防范说明P262
WGK3
RTECSMQ3325000
TSCA
D8375Sigma-Aldrich2-Deoxy-D-glucose≥98% (GC), crystalline616.75元/10 MG;   2149.72元/1 G;   7206.76元/5 G;   10000元/25 G;   32097元/100 G;   咨询

产品说明

应用

2-脱氧-D-葡萄糖(2-DG)用于缺乏葡萄糖补给的研究,以调用和研究反调节反应(CRR)的过程。2-脱氧-D-葡萄糖用于涉及放射和化学敏化以及氧化应激的抗癌策略开发中。

包装

10 mg in glass bottle
1, 5, 25, 100 g in poly bottle
无底玻璃瓶。内含物装在插入的融合锥内。

生化/生理作用

2-脱氧-D-葡萄糖(2-脱氧葡萄糖)是一种葡萄糖类似物,可通过作用于己糖激酶这一糖酵解限速步骤来抑制糖酵解。 它会被己糖激酶磷酸化为不能被磷酸葡萄糖异构酶进一步代谢的2-DG-P。 这将导致2-DG-P在细胞中的集聚以及细胞ATP的缺失。在体外,2-脱氧葡萄糖已显示出可诱导自噬、提高ROS的产生并激活AMPK。

基本信息

经验(实验)分子式C6H12O5
分子量164.16
Beilstein1723331
EC 号205-823-0
MDL编号MFCD00151328
PubChem化学物质编号24894205
NACRESNA.25

产品性质

质量水平200
生物来源synthetic
测定≥98% (GC)
形式crystalline
technique(s)gas chromatography (GC): suitable
颜色 white to off-white
mp146-147 ℃ (lit.)
溶解性H2O: 0.250 g/5mL
储存温度2-8℃
SMILES stringOC[C@@H](O)[C@@H](O)[C@H](O)CC=O
InChI1S/C6H12O5/c7-2-1-4(9)6(11)5(10)3-8/h2,4-6,8-11H,1,3H2/t4-,5-,6+/m1/s1
InChI keyVRYALKFFQXWPIH-PBXRRBTRSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
024330Fluorochem2-Deoxy-D-glucose98%242元/1g;   594元/5g;   2640元/25g;   9504元/100g;   咨询

基本信息

CAS Number154-17-6
MDL NumberMFCD00151328
Melting Point146-147℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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