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CAS: 1483-01-8
分子式: C7H16N4O2.HCl
分子量: 224.69
熔点: 213-215℃
中文名称: 
高精氨酸盐酸盐
L-高精氨酸盐酸盐
英文名称: 
l(+)-homoarginine hydrochloride
L-HOMOARGININE HYDROCHLORIDE
Homoarginine hydrochloride
(S)-2-Amino-6-guanidinohexanoic acid hydrochloride
推荐供应商
货号品牌产品名称规格包装、参考价格
L794198MACKLINL-高精氨酸盐酸盐10mM in Water186元/1ml;   咨询
储存:-20°C
L810763MACKLINL-高精氨酸盐酸盐98%30元/1g;   84元/5g;   403元/25g;   咨询
储存:2~8°C
状态:白色到灰白色粉末
H1172TCIL-Homoarginine Hydrochloride>97.0%(T)450元/1G;   1390元/5G;   咨询

基本信息

纯度/分析方法>97.0%(T)
分子式/分子量C7H16N4O2・HCl = 224.69
外观与形状(20℃)固体
Reaxys-RN4016621
PubChem物质ID87558664
MDL编号MFCD00012622

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 97.0 %
Specific rotation [a]20/D+16.0 to +20.0 deg(C=8,6N HCl)

物性(参考值)

熔点206 ℃
比旋光度 [α]D18° (C=8.6N,HCl)
水溶性可溶
242769J&KH-HArg-OH·HCl98%390元/1G;   724元/5G;   咨询

基本信息

分子式C7H16N4O2·HCl
分子量224.69
熔点213-215
MDL编码MFCD00012622
Beilstein4016621
EINECS 编号216-045-6

安全信息

防范说明P262
WGK3
TSCA
H27387Alfa AesarL-Homoarginine Hydrochloride98%754元/1g;   1128元/5g;   2440元/25g;   咨询

应用
An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.

备注
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. Refrigerated(2-7?°C).

基本信息

MDL
MFCD00012622

EINECS
216-045-6

分子式
C7H16N4O2?HCl

分子量
224.69

熔点
213-215°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in water(50 mg/mL).

Beilstein
4016621

安全信息

TSCA

C16909Alfa AesarL(+)-Homoarginine hydrochloride98%1199元/1g;   3319元/5g;   咨询

基本信息

Ref#
16909

MDL
12622

分子式
C7 H16 N4 O2 . H Cl

分子量
224.69

H1007Sigma-AldrichL-Homoarginine hydrochlorideunnatural arginine analog3915.82元/5 G;   咨询

产品说明

应用

L-高精氨酸可用于产生非天然蛋白质,用于翻译后蛋白质修饰的研究。精氨酸残基常位于蛋白质和酶的活性中心。将这些精氨酸替换为高精氨酸有助于阐明蛋白质的功能和结构要求。L-高精氨酸用于研究细胞通过一氧化氮合酶 (s) 产生一氧化氮的机制。L-高精氨酸用作选择性哺乳动物碱性磷酸酶同工酶抑制剂。高精氨酸取代精氨酸或赖氨酸使蛋白质对胰蛋白酶水解产生抗性。
高精氨酸取代精氨酸或赖氨酸使蛋白质对胰蛋白酶的蛋白水解具有抗性。精氨酸残基常位于蛋白质和酶的活性中心。将这些精氨酸替换为高精氨酸有助于阐明蛋白质的功能和结构要求。

包装

5 g in poly bottle

生化/生理作用

高精氨酸是组织非特异性碱性磷酸酶 (TNALP) 的抑制剂。也是通过钠非依赖性高亲和力 y + 转运体进行精氨酸细胞转运的抑制剂。

基本信息

线性分子式H2NC(=NH)NH(CH2)4CH(NH2)CO2H · HCl
分子量224.69
Beilstein4016621
EC 号216-045-6
MDL编号MFCD00012622
PubChem化学物质编号24895420
NACRESNA.26

产品性质

质量水平200
测定≥98% (TLC)
形式powder
颜色 white to off-white
mp213-215 ℃ (lit.)
溶解性H2O: soluble
application(s)peptide synthesis
SMILES stringCl[H].N[C@@H](CCCCNC(N)=N)C(O)=O
InChI1S/C7H16N4O2.ClH/c8-5(6(12)13)3-1-2-4-11-7(9)10;/h5H,1-4,8H2,(H,12,13)(H4,9,10,11);1H/t5-;/m0./s1
InChI keyYMKBVNVCKUYUDM-JEDNCBNOSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
M03208FluorochemH-HomoArg-OH HCl>95%264元/5g;   418元/10g;   968元/25g;   3674元/100g;   咨询

基本信息

CAS Number1483-01-8
MDL NumberMFCD00012622
Melting Point213 - 215 ℃
Density1.4

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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