CAS 132907-72-3; 雷莫司琼; (1-methyl-1h-indol-3-yl)(4,5,6,7-tetrahydro-1h-benzimidazol-5-yl)-methanon

CAS:

132907-72-3

分子式:

C₁₇H₁₈ClN₃O

分子量:

315.8

中文名称:

雷莫司琼

英文名称:

(1-methyl-1h-indol-3-yl)(4,5,6,7-tetrahydro-1h-benzimidazol-5-yl)-methanon

(R)-monohydrochlorid

(R)-5-((1-methyl-3-indolyl)carbonyl)-4,5,6,7-tetrahydro-1h-benzimidazole hydr

ramosetron

ym 060

ym060

(1-methyl-1h-indol-3-yl)(4,5,6,7-tetrahydro-1h-benzimidazol-5-yl)-,monohydrochloride, (R)-methanon

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

R796261

MACKLIN

盐酸雷莫司琼

10mM in DMSO

185元/1ml;

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储存：-20°C

R848422

MACKLIN

盐酸雷莫司琼

98%

199元/50mg; 456元/250mg; 1600元/1g;

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储存：室温,干燥
状态：白色到米黄色粉末

SML0674

Sigma-Aldrich

Ramosetron hydrochloride

≥98% (HPLC)

841.96元/10 MG; 3411.82元/50 MG;

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产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Ramosetron is a tetra hydrobenzimidazole derivative, containing an indole ring. It inhibits colon contraction mediated by serotonin, competitively.
Ramosetron hydrochloride is a potent serotonin 5-HT3 receptor antagonist with higher afinity for the 5-HT3 receptor than other currently available antagonists. Ramosetron is used clinically both as an antiemetic to treat nausea and vomiting following chemotherapy or after surgery, and in treatment of irritable bowel syndrome.

基本信息

经验(实验)分子式	C₁₇H₁₇N₃O · HCl
分子量	315.80
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -40 to -45°, c = 1 in methanol
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 20 mg/mL, clear
储存温度	−20℃
InChI	1S/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1
InChI key	XIXYTCLDXQRHJO-RFVHGSKJSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable