CAS 1269802-97-2; nhi-2 - �뵺�羺�ٷ��ַ

位置：首页 > 资料中心 > 化工字典 > 1269802-97-2

CAS:

1269802-97-2

分子式:

C₁₇H₁₂F₃NO₃

分子量:

335.28

英文名称:

nhi-2

methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1h-indole-2-carboxylate

1-hydroxy-6-phenyl-4-(trifluoromethyl)-1h-indole-2-carboxylic acid methyl ester

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

M726745

MACKLIN

1-羟基-6-苯基-4-(三氟甲基)-1H-吲哚-2-羧酸甲酯

99%

2784元/25mg;

咨询

储存：2-8°C, 干燥

SML1463

Sigma-Aldrich

NHI-2

≥98% (HPLC)

1260.64元/5 MG; 5077.25元/25 MG;

咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

NHI-2 is an inihbitor of Lactate dehydrogenase-A (LDH-A, LDHA), a key enzyme necessary to sustain glycolysis, the major pathway used by many cancer cells for cell growth and proliferation (the Warburg effect). NHI-2 has anti-glycolytic activity against a variety of cancer cells. NHI-2 inhibited cell growth of pancreatic cancer LPC006 and PANC-1 cells and enhanced the antiproliferative effects of Gemcitabine and caused apoptosis in colon cancer HCT116 cells.
NHI-2 possesses highr cell permeability.

基本信息

经验(实验)分子式	C₁₇H₁₂F₃NO₃
分子量	335.28
PubChem化学物质编号	329825897
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	ON(C(C(OC)=O)=C1)C2=C1C(C(F)(F)F)=CC(C3=CC=CC=C3)=C2
InChI	1S/C17H12F3NO3/c1-24-16(22)15-9-12-13(17(18,19)20)7-11(8-14(12)21(15)23)10-5-3-2-4-6-10/h2-9,23H,1H3
InChI key	YPPFWRWCZNXINO-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9