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CAS: 12192-57-3
分子式: C6H11AuO5S
分子量: 392.17
中文名称: 
硫代葡糖金
英文名称: 
aurotan
aurothioglucose
aurumine
authron
brenol
glysanol b
gold thioglucose
(d-glucopyranosylthio)-gol
gtg
oronol
romosol
skf 10056
solganal
solganal b
thioglucose d'or
(1-thio-d-glucopyranosato)-gol
(1-d-glucosylthio)gold
(1-thio-d-glucopyranosato)gold
(d-glucopyranosylthio)gold
1-aurothio-d-glucopyranose
1-thio-d-glucopyranose, gold complex
1-thio-d-glucopyranose, monogold(1+) salt
1-thio-glucopyranose, monogold(1+) salt
aureotan
auromyose
展开更多英文名
用途: Aurothioglucose (Gold thioglucose) 是众所周知的TrxR1活性位点抑制剂,它能抑制hela细胞中的 TrxR1活性同时对细胞活性无影响。
推荐供应商
货号品牌产品名称规格包装、参考价格
A883897MACKLINAurothioglucose98%2455元/1mg;   咨询
储存:2-8℃
状态:白色到米黄色粉末
A0606Sigma-AldrichAurothioglucose hydrate≥96% (titration)1379.75元/5 MG;   4915.84元/25 MG;   咨询

产品说明

应用

Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice.

包装

5, 25 mg in glass bottle

生化/生理作用

Aurothioglucose, a gold compound used clinically to treat rheumatoid arthritis, has recently been found to be a potent PKCiota-Par6 interaction inhibitor, with an IC50 approximately 1 μM. Disruption of this interaction disrupts a rac1 signaling pathway that is required for transformed growth in non-small-cell lung cancer.

特点和优势

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C6H11AuO5S · xH2O
分子量392.18 (anhydrous basis)
EC 号235-365-7
PubChem化学物质编号24724383
NACRESNA.77

产品性质

质量水平100
测定≥96% (titration)
形式powder
储存条件desiccated
颜色 white to beige
溶解性H2O: 5 mg/mL, clear
储存温度2-8℃
SMILES stringO.OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O
InChI1S/C6H12O5S.Au.H2O/c7-1-2-3(8)4(9)5(10)6(12)11-2;;/h2-10,12H,1H2;;1H2/q;+1;/p-1/t2-,3-,4+,5-,6-;;/m1../s1
InChI keySGVIEHTYEMEDRR-PKXGBZFFSA-M

安全信息

象形图GHS08
警示用语:Danger
危险声明H317 - H334
预防措施声明P261 - P280 - P342 + P311
危险分类Resp. Sens. 1 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
1045508USPAurothioglucoseUnited States Pharmacopeia (USP) Reference Standard5085元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C6H11AuO5S
分子量392.18
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
InChI1S/C6H12O5S.Au/c7-1-2-3(8)4(9)5(10)6(12)11-2;/h2-10,12H,1H2;/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1
InChI keyXHVAWZZCDCWGBK-WYRLRVFGSA-M

安全信息

象形图GHS08
警示用语:Danger
危险声明H317 - H334
预防措施声明P261 - P280 - P284 - P304 + P340 - P342 + P311
危险分类Resp. Sens. 1 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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