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CAS: 1131-01-7
分子式: C10H12ClNO
分子量: 197.67
熔点: 143-148℃
中文名称: 
2,6-二甲基氯代乙酰苯胺
N-氯乙酰-2,6-二甲基苯胺
2-氯-N-(2,6-二甲苯基)乙酰胺
英文名称: 
2-chloro-n-(2,6-dimethylphenyl)-acetamid
2-chloro-n-(2,6-dimethylphenyl)acetamide
2-Chloro-2',6'-acetoxylidide
N-Chloroacetyl-2,6-dimethylaniline
Chloroaceto-2,6-xylidide
à-Chloro-2,6-dimethylacetanilide
2-Chloro-2',6'-acefoxylidide
性质描述: 熔点150-151℃。
生产方法: 由2,6-二甲基苯胺与氯乙酰氯反应而得:将无水苯及2,6-二甲基苯胺冷却至28℃以下,在搅拌下缓缓滴入氯乙酰氯,温度不超过30℃,加毕,搅拌反应1h,再加热回流8h。冷却结晶,甩滤,干燥得成品。
用途: 用作医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
C833688MACKLIN2-氯-N-(2,6-二甲苯基)乙酰胺98%33元/2g;   63元/10g;   368元/100g;   1230元/500g;   咨询
储存:室温,密封,干燥
状态:白色到淡黄色粉末
C2307TCI2-Chloro-2',6'-dimethylacetanilide>98.0%(GC)(N)310元/5G;   640元/25G;   咨询

基本信息

纯度/分析方法>98.0%(GC)(N)
分子式/分子量C10H12ClNO = 197.66
外观与形状(20℃)固体
Reaxys-RN781309
PubChem物质ID87560890
MDL编号MFCD00000926

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystal
Purity(GC)min. 98.0 %
Purity(with Total Nitrogen)min. 98.0 %
Melting point146.0 to 150.0 ℃

物性(参考值)

熔点148 ℃
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
165744J&K2-Chloro-N-(2,6-dimethylphenyl)acetamide98%81元/5G;   149元/25G;   咨询

基本信息

分子式C10H12ClNO
分子量197.67
熔点150-151
MDL编码MFCD00000926
Beilstein781309
EINECS 编号214-460-7

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
TSCA
L02727Alfa Aesar2-Chloro-2',6'-dimethylacetanilide99%1198元/10g;   4720元/50g;   咨询

应用
2-Chloro-2',6'-dimethylacetanilide is used in the determination of the enantiomers of tocainide in blood plasma by gas-liquid chromatography with electron-capture detection. It is a nonsteroidal antinflammatory drug.

备注
Keep the container tightly closed in a cool, dry and well ventilated place. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00000926

EINECS
214-460-7

分子式
C10H12ClNO

分子量
197.67

熔点
143-148°

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in Chloroform, Methanol. Insoluble in water.

Beilstein
781309

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P280g-P305+P351+P338
Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA

194921Sigma-AldrichN-(2,6-Dimethylphenyl)chloroacetamide99%646.38元/10 G;   咨询

产品说明

一般描述

N- (2,6-二甲基苯基)氯乙酰胺(2-氯-2',6'-乙酰氧基)是非甾体类抗炎药。

应用

N- (2,6-二甲基苯基)氯乙酰胺(2-氯-2',6'-乙酰氧基),用气相色谱电子捕获检测法同时测定血浆中妥卡尼的对映体 。

包装

10 g in poly bottle

基本信息

线性分子式ClCH2CONHC6H3(CH3)2
分子量197.66
EC 号214-460-7
MDL编号MFCD00000926
PubChem化学物质编号24851662
NACRESNA.22

产品性质

质量水平100
测定99%
mp150-151 ℃ (lit.)
SMILES stringCc1cccc(C)c1NC(=O)CCl
InChI1S/C10H12ClNO/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6H2,1-2H3,(H,12,13)
InChI keyFPQQSNUTBWFFLB-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR1673SupelcoLidocaine Related Compound HPharmaceutical Secondary Standard; Certified Reference Material9640.24元/100 MG;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2078 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式ClCH2CONHC6H3(CH3)2
分子量197.66
EC 号214-460-7
MDL编号MFCD00000926
PubChem化学物质编号329823547
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 100 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp150-151 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1366080
储存温度2-30℃
SMILES stringCc1cccc(C)c1NC(=O)CCl
InChI1S/C10H12ClNO/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6H2,1-2H3,(H,12,13)
InChI keyFPQQSNUTBWFFLB-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1366080USPLidocaine Related Compound HUnited States Pharmacopeia (USP) Reference Standard10218.8元/50 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式ClCH2CONHC6H3(CH3)2
分子量197.66
MDL编号MFCD00000926
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp150-151 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCc1cccc(C)c1NC(=O)CCl
InChI1S/C10H12ClNO/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6H2,1-2H3,(H,12,13)
InChI keyFPQQSNUTBWFFLB-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
068295Fluorochem2-Chloro-N-(2,6-dimethylphenyl)acetamide97%242元/10g;   550元/25g;   1078元/100g;   咨询

基本信息

CAS Number1131-01-7
MDL NumberMFCD00000926
Melting Point143-148℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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