CAS 1104546-89-5; byk204165 - �뵺�羺�ٷ��ַ

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

M793766

MACKLIN

4-((1-甲基-1H-吡咯-2-基)亚甲基)异喹啉-1, 3(2H, 4H)-二酮

10mM in DMSO

720元/1ml;

咨询

储存：-20°C

M918751

MACKLIN

4-((1-甲基-1H-吡咯-2-基)亚甲基)异喹啉-1,3(2H,4H)-二酮

98%

151元/5mg; 509元/25mg; 1280元/100mg; 2176元/250mg;

咨询

储存：2-8°C，密闭，干燥
状态：黄色到红色粉末或晶体

B3188

Sigma-Aldrich

BYK204165

≥98% (HPLC)

1480.38元/5 MG; 7260.65元/25 MG;

咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

BYK204165 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1). It is 100-fold selective for PARP-1 over PARP-2.

基本信息

经验(实验)分子式	C₁₅H₁₂N₂O₂
分子量	252.27
MDL编号	MFCD12912397
PubChem化学物质编号	329773214
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	yellow
溶解性	DMSO: >20 mg/mL
储存温度	2-8℃
SMILES string	Cn1cccc1\C=C2/C(=O)NC(=O)c3ccccc23
InChI	1S/C15H12N2O2/c1-17-8-4-5-10(17)9-13-11-6-2-3-7-12(11)14(18)16-15(13)19/h2-9H,1H3,(H,16,18,19)/b13-9-
InChI key	BTYSIDSTHDDAJW-LCYFTJDESA-N
Gene Information	human ... PARP1(142) mouse ... PARP1(11545) rat ... PARP1(25591)

安全信息

象形图
警示用语：	Warning
危险声明	H317
预防措施声明	P280
危险分类	Skin Sens. 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

528824

Sigma-Aldrich

PARP Inhibitor XIV-CAS 1104546-89-5-Calbiochem

The PARP Inhibitor XIV, also referenced under CAS 1104546-89-5, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

4399.61元/10 MG;

咨询

产品说明

一般描述

A cell-permeable isoquinolinedione compound that potently inhibits PARP-1 activity (pIC₅₀ = 7.35; IC₅₀ = 45 nM) in a NAD⁺-competitive and reversible manner, while affecting PPAR-2 activity with a 100-fold lower potency. Selectively inhibits PARP-1-mediated cellular PAR formation and is of little effect against PAR formation in fibroblasts derived from parp-1(-/-) mice. Its in vivo application is limited by a poor aqueous solubility (~9 µM).

包装

10 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Eltze, T., et al. 2008. Mol. Pharmacol.74, 1587.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₁₅H₁₂N₂O₂
分子量	252.27
MDL编号	MFCD12912397

产品性质

质量水平	100
测定	≥97% (sum of two isomers, HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze protect from light
颜色	orange
溶解性	DMSO: 10 mg/mL
运输	ambient
储存温度	2-8℃

安全信息

象形图
警示用语：	Warning
危险声明	H317
预防措施声明	P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
危险分类	Skin Sens. 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable