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CAS: 1031206-36-6
分子式: C18H16O4
分子量: 296.32
沸点: 535.7±50.0 °C(Predicted)
英文名称: 
ims2186
3-[1-(3-hydroxy-4-methoxyphenyl)-meth-(e)-ylidene]-6-methyl-chroman-4-one
推荐供应商
货号品牌产品名称规格包装、参考价格
E737519MACKLIN(E)-3-(3-羟基-4-甲氧基亚苄基)-6-甲基苯并二氢吡喃-4-酮98%658元/5mg;   2773元/25mg;   5280元/50mg;   咨询
储存:2-8°C, 密封, 干燥
状态:固体
I7160Sigma-AldrichIMS2186≥98% (HPLC), solid1143.83元/5 MG;   咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

IMS2186 is an anti-proliferative and anti-angiogenic agent. Apparently IMS2186 blocks the cell cycle at G2 and inhibits the production of PGE2/TNF-α. IMS2186 inhibits cell growth in vitro in tumor cells, non-transformed fibroblasts, and retinal pigment epithelial cells. IMS2186 inhibits angiogenesis (IC50 = 0.1 μM) and cell migration. Intraocular injection of IMS2186 could be a long-lasting effective treatment for CNV (choroidal neovascularization) in AMD (age-related macular degeneration) with a reduction in scarring and related visual loss.

基本信息

经验(实验)分子式C18H16O4
分子量296.32
MDL编号MFCD12912419
PubChem化学物质编号329815315
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
储存条件desiccated
颜色 white to off-white
溶解性DMSO: >20 mg/mL
储存温度room temp
SMILES stringCOc1ccc(cc1O)\C=C2/COc3ccc(C)cc3C2=O
InChI1S/C18H16O4/c1-11-3-5-16-14(7-11)18(20)13(10-22-16)8-12-4-6-17(21-2)15(19)9-12/h3-9,19H,10H2,1-2H3/b13-8+
InChI keyBZCADTHMZLYKAR-MDWZMJQESA-N

安全信息

象形图GHS09
警示用语:Warning
危险声明H400
预防措施声明P273
危险分类Aquatic Acute 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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