CAS 101303-98-4; zacopride hydrochloride hydrate

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CAS:

101303-98-4

分子式:

C₁₅H₂₁Cl₂N₃O₂

分子量:

346.26

熔点:

158-160 °C

英文名称:

zacopride hydrochloride hydrate

4-amino-n-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride hydrate

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

Z982422

MACKLIN

Zacopridehydrochloride

97%

1414元/10mg; 2880元/25mg;

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储存：2-8°C, 干燥

SML0081

Sigma-Aldrich

Zacopride hydrochloride hydrate

≥98% (HPLC)

1607.61元/10 MG; 6476.67元/50 MG;

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产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Zacopride is a sub-nanomolar antagonist of the serotonin 5-HT3 receptor that also displays agonist-like activity against 5-HT4 receptors. It is a potent anxiolytic in animal models, and also has strong antiemetic effects, and also increases aldosterone levels via activation of 5-HT4 receptor in the adrenal glands.

特点和优势

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₁₅H₂₀ClN₃O₂ · HCl · xH₂O
分子量	346.25 (anhydrous basis)
MDL编号	MFCD20488057
PubChem化学物质编号	329825143
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to tan
溶解性	H₂O: ≥10 mg/mL
创始人	Wyeth
储存温度	2-8℃
SMILES string	O.Cl.COc1cc(N)c(Cl)cc1C(=O)NC2CN3CC[C@H]2CC3
InChI	1S/C15H20ClN3O2.ClH.H2O/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19;;/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20);1H;1H2
InChI key	NPXXKMBXEODDAF-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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