靶标９�p style="text-indent: 2em;">Jmjd1c

产品别名９�p style="text-indent: 2em;">5430433L24Rik� D630035I23Rik� Jmjdic� TRIP8� Jmjd1c� jumonji domain containing 1C� jumonji domain containing 1C� probable JmjC domain-containing histone demethylation protein 2C� jumonji domain-containing protein 1C� 甲状腺受体相互作用蛋�?�

背景信息９�div style="text-indent: 2em;">The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants.