靶标９�p style="text-indent: 2em;">Plpp6

产品别名９�p style="text-indent: 2em;">4932443D16Rik� Ppapdc2� Plpp6� phospholipid phosphatase 6� phospholipid phosphatase 6� polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6� phosphatidic acid phosphatase type 2 domain containing 2� phosphatidic acid phosphatase type 2 domain-containing protein 2� presqualene diphosphate phosphatase�

背景信息９�div style="text-indent: 2em;">PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.