靶标９�p style="text-indent: 2em;">MARCHF4

产品别名９�p style="text-indent: 2em;">MARCH-IV� MARCH4� RNF174� MARCHF4� membrane associated ring-CH-type finger 4� membrane associated ring-CH-type finger 4� E3 ubiquitin-protein ligase MARCHF4� E3 ubiquitin-protein ligase MARCH4� RING finger protein 174� RING-type E3 ubiquitin transferase MARCH4� RING-type E3 ubiquitin transferase MARCHF4� membrane associated ring finger 4� membrane-associated RING finger protein 4� membrane-associated RING-CH protein IV� membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase� 膜相关环指蛋�?�

背景信息９�div style="text-indent: 2em;">MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010],