靶标９�p style="text-indent: 2em;">Slc37a2

产品别名９�p style="text-indent: 2em;">G3PP� Slc37a1� cI-2� ci2� Slc37a2� solute carrier family 37 (glycerol-3-phosphate transporter), member 2� solute carrier family 37 (glycerol-3-phosphate transporter), member 2� glucose-6-phosphate exchanger SLC37A2� cAMP inducible 2 protein� cAMP inducible gene 2� cAMP-inducible protein 2� solute carrier family 37 (glycerol-3-phosphate transporter), member 1� solute carrier family 37 member 2� sugar phosphate exchanger 2� 溶质载体转运蛋白家族37成员A2�

背景信息９�div style="text-indent: 2em;">The Slc37 gene family consists of four members which have 10-12 predicted transmembrane domains and belong to the sugar-phosphate transporter superfamily. Recent experiments have demonstrated that Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. Its transcript is also expressed in spleen and thymus and the cell lines RAW264.7 and THP-1. Compared to wild-type mice, Slc37A2 mRNA is expressed at nine-fold higher levels in abdominal epididymal fat deposits of ob/ob mice, suggesting that it may be required to limit the contribution of macrophages to the inflammatory state present in obesity. Slc37A2 protein is post-translationally modified with the addition of N-linked glycans and migrates as a heterogeneous species of 50-75kDa.