靶标９�p style="text-indent: 2em;">Vkorc1

产品别名９�p style="text-indent: 2em;">D7Wsu86e� Vkorc1� vitamin K epoxide reductase complex, subunit 1� vitamin K epoxide reductase complex, subunit 1� vitamin K epoxide reductase complex subunit 1� phylloquinone epoxide reductase� vitamin K 2,3-epoxide reductase complex subunit 1� vitamin K epoxide reductase subunit I� vitamin K1 2,3-epoxide reductase subunit 1� vitamin K1 epoxide reductase (warfarin-sensitive)�

背景信息９�div style="text-indent: 2em;">VKORC1 Antibody: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.