靶标９�p style="text-indent: 2em;">SLC12A6

产品别名９�p style="text-indent: 2em;">ACCPN� KCC3� KCC3A� KCC3B� SLC12A6� solute carrier family 12 member 6� solute carrier family 12 member 6� solute carrier family 12 member 6� K-Cl cotransporter 3� electroneutral potassium-chloride cotransporter 3� potassium chloride cotransporter 3� potassium chloride cotransporter KCC3a-S3� potassium-chloride transporter-3a� potassium-chloride transporter-3b� solute carrier family 12 (potassium/chloride transporter), member 6� solute carrier family 12 (potassium/chloride transporters), member 6� 钾氯协同转运蛋白3(KCC3)� 钾氯离子转运蛋白3�

背景信息９�div style="text-indent: 2em;">Solute carrier family 12(potassium/chloride transporters), member 6, also called SLC12A6 or KCC3, is a protein that in humans is encoded by the SLC12A6 gene. This gene is a member of the K-Cl cotransporter(KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. By radiation hybrid and somatic cell hybrid analyses, this gene is mapped to 15q14. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.