靶标９�p style="text-indent: 2em;">ENDOU

产品别名９�p style="text-indent: 2em;">P11� PP11� PRSS26� ENDOU� endonuclease, poly(U) specific� endonuclease, poly(U) specific� uridylate-specific endoribonuclease� 22 serine protease� 26 serine protease� endonuclease, polyU-specific� placental protein 11� poly(U)-specific endoribonuclease� protein endoU� 胎盘蛋白11�

背景信息９�div style="text-indent: 2em;">Endonuclease, poly(U) specific is a protein that in humans is encoded by the ENDOU gene. This gene encodes a protein with endoribonuclease activity that binds polyuridine-enriched single-stranded RNA. This gene was initially characterized based on its high expression in placenta but was mischaracterized as a serine protease. In mouse, this gene promotes tolerance to self-antigens by regulating B cell activation-induced cell death (AICD). The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.