靶标９�p style="text-indent: 2em;">LTBP4

产品别名９�p style="text-indent: 2em;">ARCL1C� LTBP-4� LTBP4L� LTBP4S� LTBP4� latent transforming growth factor beta binding protein 4� latent transforming growth factor beta binding protein 4� latent-transforming growth factor beta-binding protein 4� latent transforming growth factor-beta binding protein 4L� 转化生长因子β结合蛋白4�

背景信息９�div style="text-indent: 2em;">Transforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]