靶标９�p style="text-indent: 2em;">SLC19A1

产品别名９�p style="text-indent: 2em;">CHMD� FOLT� IFC-1� IFC1� MEGAF� REFC� RFC� RFC1� RFT-1� hRFC� hSLC19A1� SLC19A1� solute carrier family 19 member 1� solute carrier family 19 member 1� reduced folate transporter� folate transporter 1� intestinal folate carrier 1� placental folate transporter� reduced folate carrier 1� reduced folate carrier protein� reduced folate transporter 1� solute carrier family 19 (folate transporter), member 1� 叶酸转运蛋白(FOLT)� 溶质载体家族蛋白19成员A1�

背景信息９�div style="text-indent: 2em;">Solute carrier family 19 (folate transporter), member 1, also known as SLC19A1 or RFC1, is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. And RFC1 plays a role in maintaining intracellular concentrations of folate.