靶标９�p style="text-indent: 2em;">RFX1

产品别名９�p style="text-indent: 2em;">EFC� RFX� RFX1� regulatory factor X1� regulatory factor X1� MHC class II regulatory factor RFX1� MHC class II regulatory factor RFX� enhancer factor C� regulatory factor X, 1 (influences HLA class II expression)� trans-acting regulatory factor 1� transcription factor RFX1�

背景信息９�div style="text-indent: 2em;">This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE).