靶标９�p style="text-indent: 2em;">NFE2

产品别名９�p style="text-indent: 2em;">NF-E2� p45� NFE2� nuclear factor, erythroid 2� nuclear factor, erythroid 2� transcription factor NF-E2 45 kDa subunit� leucine zipper protein NF-E2� nuclear factor (erythroid-derived 2), 45kD� nuclear factor (erythroid-derived 2), 45kDa� nuclear factor, erythroid-derived 2 45 kDa subunit�

背景信息９�div style="text-indent: 2em;">function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 bZIP domain.,subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity). Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis.,tissue specificity:Expressed in hematopoietic cells and also in colon and testis.,