靶标９�p style="text-indent: 2em;">KLRC3

产品别名９�p style="text-indent: 2em;">NKG2-E� NKG2E� KLRC3� killer cell lectin like receptor C3� killer cell lectin like receptor C3� NKG2-E type II integral membrane protein� NK cell receptor E� NKG2-E-activating NK receptor� killer cell lectin-like receptor subfamily C, member 3� 杀伤细胞凝集素样受体C亚家族成�?�

背景信息９�div style="text-indent: 2em;">Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.