靶标９�p style="text-indent: 2em;">KCNQ3

产品别名９�p style="text-indent: 2em;">BFNC2� EBN2� KV7.3� KCNQ3� potassium voltage-gated channel subfamily Q member 3� potassium voltage-gated channel subfamily Q member 3� potassium voltage-gated channel subfamily KQT member 3� potassium channel subunit alpha KvLQT3� potassium channel, voltage gated KQT-like subfamily Q, member 3� potassium channel, voltage-gated, subfamily Q, member 3� potassium voltage-gated channel, KQT-like subfamily, member 3� voltage-gated potassium channel subunit Kv7.3� 电压门控钾通道亚基Kv7.3�

背景信息９�div style="text-indent: 2em;">This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants.