靶标９�p style="text-indent: 2em;">IARS1

产品别名９�p style="text-indent: 2em;">GRIDHH� IARS� ILERS� ILRS� IRS� PRO0785� IARS1� isoleucyl-tRNA synthetase 1� isoleucyl-tRNA synthetase 1� isoleucine--tRNA ligase, cytoplasmic� isoleucine tRNA ligase 1, cytoplasmic� 异亮氨酰tRNA合成�?IARS)�

背景信息９�div style="text-indent: 2em;">Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.