靶标９�p style="text-indent: 2em;">HOXD11

产品别名９�p style="text-indent: 2em;">HOX4� HOX4F� HOXD11� homeobox D11� homeobox D11� homeobox protein Hox-D11� Hox-4.6, mouse, homolog of� homeo box 4F� homeo box D11� homeobox protein Hox-4F� 同源盒蛋白D11�

背景信息９�div style="text-indent: 2em;">This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis. [provided by RefSeq, Jul 2008],